Thermal denaturation of ZIKV NS2B/NS3^pro and CHIKV nsP2^pro using fluorescence spectroscopy. by Raphael J. Eberle (9286932)

Free energy landscape (FEL) analysis for the SP domain of native PC and its mutant structures over 200 ns MD simulation times. by Mahvash Farajzadeh-Dehkordi (17468232)

Structural details for each point mutation studied by X-ray crystallography in this study. by Aleksi Sutinen (10039145)

Subjects:

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant by Ittipat Meewan (7455041)

“…Several drugs targeting the protease have been developed, but drug-resistant mutant strains emerged. Here, we screened a library and synthesized a novel class of small molecules based on a tryptophan derivative scaffold identified as HCV NS3/4A protease inhibitors that are active against both wild type and mutant form of the protease. …”

MMP-2 production is decreased following ALK5 inhibition. by Rebecca A. Scott (488956)

Decreased echinocandin susceptibility in <i>Candida parapsilosis</i> causing candidemia and emergence of a pan-echinocandin resistant case in China by Yating Ning (11264310)

Heterocene Catalysts and Reaction Temperature Gradient in Dec-1-ene Oligomerization for the Production of Low Viscosity PAO Base Stocks by Ilya E. Nifant’ev (1561813)

“…A gradual decrease of the oligomerization temperature as dec-1-ene was consumed resulted in decreased dimer formation (down to 10%) and increased oligomer yields (up to 84%). …”

Advancing the science of NOWS research. by Sarah E. Maylott (14560785)

“…<div><p>Every 15 minutes in the US, an infant exposed to opioids is born. Approximately 50% of these newborns will develop Neonatal Opioid Withdrawal Syndrome (NOWS) within 5 days of birth. …”

Protocol measures. by Sarah E. Maylott (14560785)

“…<div><p>Every 15 minutes in the US, an infant exposed to opioids is born. Approximately 50% of these newborns will develop Neonatal Opioid Withdrawal Syndrome (NOWS) within 5 days of birth. …”

Cry variables. by Sarah E. Maylott (14560785)

“…<div><p>Every 15 minutes in the US, an infant exposed to opioids is born. Approximately 50% of these newborns will develop Neonatal Opioid Withdrawal Syndrome (NOWS) within 5 days of birth. …”

Metformin/rifampicin combination decreases <i>S</i>. <i>aureus</i> load and persisters in Mice. by Xiao-Qi Lin (9548375)

Competition localization increases with growth rate or the distances between colonies, and decreases with the resource diffusion constant. by Jeremy M. Chacón (8259792)

AIM-100 reduces dsRNA silencing in body wall muscle and decreases DA neurodegeneration. by Anthony L. Gaeta (13272609)

Origin firing efficiency is decreased for all replication origins when Pol α levels are reduced. by Sarina Y. Porcella (8811746)

Change from full-scale to reduced model in sum (across all time points and grids) of squared error between simulation and MC scan data as a function of threshold elevation. by Monica E. Shapiro (22622240)

Instantaneous RSSI of EOPAPS and the proposed eHMP. by Khong-Lim Yap (8357256)

The retransmission rate using eHMP and EOPAPS. by Khong-Lim Yap (8357256)

Data on 1pre-treatment1 and ¹post-treatment1 tracking1 tiles reflecting1decrease in rodent1 activity¹ as a result1 of 0.0051% brodifacoum^m mixed1 i... by Durr e Shahwar (17798007)

Flow chart of the study procedures. by Kazuhiko Ikeuchi (9234268)

“…Pre-treatment spontaneous decrease of RPR titer was associated with a slower decrease in post-treatment RPR titer.…”

Aggrecan knockdown ATDC5 chondroprogenitor cells have decreased Alcian blue staining and absorbance levels compared to control cells after ITS stimulation. by Juanita K. Hodax (6848540)