Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD) by Christina W. Agudelo (8415171)

“…Mice exposed to smoke for six months recapitulated surfactant lipidomic changes observed in human subjects with COPD. In summary, we show that the surfactant lipidome is substantially altered in subjects with COPD, and decreased availability of phospholipids correlated with decreased pulmonary function. …”

Deletion of <i>sagA</i> alone results in a decrease in nasopharyngeal infection. by Blake A. Shannon (14197601)

TG6-44 treatment leads to decrease in A/X31-induced cell death in THP-1 cells. by Juan A. De La Cruz (11154187)

Image_8_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_2_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_10_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_9_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_1_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_3_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_7_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_4_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Image_6_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…The lack of characterization of the pathogenesis of psoriasis has hindered efficient clinical treatment of the disease. In our study, we observed that expression of complement component 5a receptor 1(C5aR1) was significantly increased in skin lesions of both imiquimod (IMQ) and IL23-induced psoriatic mice and patients with psoriasis. …”

Knockdown of p65 in A549 cells results in a decreased infection rate. by Janine J. Wilden (8849948)

Distribution of pulmonary ventilation assessed by center of ventilation (CoV) presented over the five time points: Induction-SB, MV-5min, MV-30min, MV-late and recovery-SB. by Milena S. Nascimento (14803681)

Fig 5 - by Arjen Tilstra (6915227)

Prenatal alcohol exposure (PAE) decreases brain and body weights at E14 and P0. by Danielle Sambo (6077924)

<i>Med23</i> deletion causes decreased H3K9me2 occupancy among the promoter of <i>Ccl5</i> and <i>Cxcl10</i>. by Zhichao Wang (3570413)

Detection of cytosine methylation by enzymatic digestion and Southern blot and confirmation of bisulfite sequencing results by PCR and Sanger sequencing. by Mareike Möller (5548745)

Subjects:

The numbers of parasite cysts in the brain decrease and the sizes increase as <i>Toxoplasma gondii</i> infection progresses in mice C57BL/6. by Leda Castaño Barrios (8524317)

DataSheet_1_Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in Asthma.pdf by Juan José Nieto-Fontarigo (11800142)

“…Background<p>Both anti-viral and anti-inflammatory bronchial effects are warranted to treat viral infections in asthma. We sought to investigate if imiquimod, a TLR7 agonist, exhibits such dual actions in ex vivo cultured human bronchial epithelial cells (HBECs), targets for SARS-CoV-2 infectivity.…”