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non decrease » point decrease (Expand Search), note decreased (Expand Search), fold decrease (Expand Search)
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we decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
e non » _ non (Expand Search), a non (Expand Search)
5 c » 25 c (Expand Search)
non decrease » point decrease (Expand Search), note decreased (Expand Search), fold decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
e non » _ non (Expand Search), a non (Expand Search)
5 c » 25 c (Expand Search)
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…<p>(A-B) GCase, (C-D) gluocosylceramide (GlcCer), and (E-F) glucosylsphingosine (GlcSph) levels measured in whole brain homogenate and liver homogenate of C57Bl/6 wild type (WT) and <i>GBA1</i> D409V KI heterozygous (HET) mice at 5 months of age (n = 10/age). …”
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The ratio between the bias in the naïve SI and shuffle SI decreases with tuning specificity, but not with sample size.
Published 2022“…(B) The bias ratio (mean ± SEM) decreases as a function of the true SI for a sample size of 1 minute (blue), 5 minutes (cyan) and 20 minutes (green). …”
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Selectivity of PRMT5 inhibition with C220.
Published 2021“…(C) Immunoblots and quantification of three biological replicate experiments, showing attenuated SDMA and H4R3me2s in 17–71 (day 4) and CLBL-1 (day 2) after treatment with 100 nM C220, with no significant decreased to PRMT5 expression. …”
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