يعرض 121 - 140 نتائج من 64,082 نتيجة بحث عن '(((( 5 ht decrease ) OR ( 5 ((nn decrease) OR (a decrease)) ))) OR ( 5 nm decrease ))', وقت الاستعلام: 0.86s تنقيح النتائج
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    Table_1_Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT1A-Mediated cAMP Signaling.DOCX حسب Jianxin Li (158332)

    منشور في 2020
    "…Background<p>Major depressive disorder (MDD) is a severe mental disorder related to the deficiency of monoamine neurotransmitters, particularly to abnormalities of 5-HT (5-hydroxytryptamine, serotonin) and its receptors. …"
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

    منشور في 2021
    "…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

    منشور في 2021
    "…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"
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    Oxytocin decreases postsynaptic CeA spontaneous GABAergic transmission and blocks presynaptic alcohol effects. حسب Brendan J. Tunstall (6593357)

    منشور في 2019
    "…<p>(A, Top) Representative GABA<sub>A</sub>-mediated sIPSCs of CeA neurons from nondependent and dependent rats prior to (baseline) and during application of oxytocin (500 nM). …"
  10. 130

    5.HT<sub>1A</sub> binding difference between known cause of death (KCOD) controls and SIDS. حسب Hannah C. Kinney (10280975)

    منشور في 2025
    "…When SIDS is compared to all KCOD controls, the HG, NTS, and MAO show a significant mean difference in 5-HT<sub>1A</sub> receptor binding. …"
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    Data_Sheet_1_Determining 5HT7R’s Involvement in Modifying the Antihyperalgesic Effects of Electroacupuncture on Rats With Recurrent Migraine.pdf حسب Lu Liu (171341)

    منشور في 2021
    "…<p>Electroacupuncture (EA) is widely used in clinical practice to relieve migraine pain. 5-HT<sub>7</sub> receptor (5-HT<sub>7</sub>R) has been reported to play an excitatory role in neuronal systems and regulate hyperalgesic pain and neurogenic inflammation. 5-HT<sub>7</sub>R could influence phosphorylation of protein kinase A (PKA)- or extracellular signal-regulated kinase<sub>1</sub><sub>/</sub><sub>2</sub> (ERK<sub>1</sub><sub>/</sub><sub>2</sub>)-mediated signaling pathways, which mediate sensitization of nociceptive neurons via interacting with cyclic adenosine monophosphate (cAMP). …"
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    The decrease or inhibition of Hsp90 induced REST degradation. حسب Raúl Orozco-Díaz (7067624)

    منشور في 2019
    "…<p>(A) Effect of Hsp90α ASO on cell viability. Differentiated SH-SY5Y cells were transfected with different concentrations of Hsp90α ASO. …"
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    Data_Sheet_1_5-HT1A Receptor Agonist Promotes Retinal Ganglion Cell Function by Inhibiting OFF-Type Presynaptic Glutamatergic Activity in a Chronic Glaucoma Model.docx حسب Xujiao Zhou (6661499)

    منشور في 2019
    "…In addition, the high expression of GS and EAAT2 induced by glaucoma was downregulated by the 5-HT1A receptor agonist 8-OH-DPAT and the 5-HT1A receptor antagonist WAY-100635, respectively. …"
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    Image1_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf حسب Allyson S. Munneke (14200148)

    منشور في 2022
    "…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …"
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    Image2_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf حسب Allyson S. Munneke (14200148)

    منشور في 2022
    "…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …"
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    Image3_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf حسب Allyson S. Munneke (14200148)

    منشور في 2022
    "…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …"
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