Effect of 5-HTR blockade on reaction time in the work/delay task. حسب Yukiko Hori (299784)

الموضوعات:

Effect of 5-HTR blockade on error pattern in the work/delay task. حسب Yukiko Hori (299784)

الموضوعات:

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs حسب Michael J. Cunningham (14267038)

"…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …"

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs حسب Michael J. Cunningham (14267038)

"…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …"

5-HT inhibits <i>P</i>. <i>berghei</i> infection in mosquitoes. حسب Li Gao (131516)

"…The purple boxes represent the metabolites of the indole pathway, the blue boxes represent the metabolites of the 5-HT pathway, and the tan boxes represent the metabolites of the kynurenine pathway. …"

Inhibiting translation in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. حسب Lisa Patricia Deliu (13570709)

Inducing proteotoxic stress in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. حسب Lisa Patricia Deliu (13570709)

Effect of 5-HTR blockade on the relationship between error rate and reaction time in the reward-size task. حسب Yukiko Hori (299784)

الموضوعات:

Genotype frequencies of the polymorphisms <i>rs1799971</i> (OPRM1), <i>rs6296</i> (5-HT_1A) and the triallelic 5-HTT for the whole group, as well as fibromyalgia (FM) pat... حسب Jeanette Tour (10790855)

5-HT- induced mitochondrial ROS inhibits <i>P</i>. <i>berghei</i> infection. حسب Li Gao (131516)

Matrix crosslinking decreases cell migration persistence. حسب Michael Pamonag (12295175)

Occupancy estimation. حسب Yukiko Hori (299784)

الموضوعات:

Decrease in vRNA in brain during antiretroviral therapy. حسب Sonny R. Elizaldi (9684796)

Normalized pressure pain thresholds (PPTs) (mean ± SEM) at start, middle, end and 5 minutes after a standardized tourniquet test. حسب Jeanette Tour (10790855)

Additional Analysis of visually induced calcium transients in Fig 5. حسب Maureen M. Sampson (9322886)

"…<p>Visually induced calcium transients were recorded in flies expressing L2-split-GAL4>GCaMP6f as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g005" target="_blank">Fig 5</a>. …"

Additional Analysis of visually induced calcium transients in Fig 6. حسب Maureen M. Sampson (9322886)

"…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …"

Decrease in ISV diameter exacerbates the decrease in WSS caused by hematocrit reduction. حسب Swe Soe Maung Ye (12895103)

Serotonin modulates L2 neuron visually induced calcium transient kinetics. حسب Maureen M. Sampson (9322886)

"…Light or dark stimuli (A, middle panel, white and black vertical bars respectively) were flashed at random every 5 s for 6 min. …"

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"