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5 w » 5 wt (Expand Search)
ht decrease » _ decrease (Expand Search), nn decrease (Expand Search), we decrease (Expand Search)
w decrease » we decrease (Expand Search), _ decrease (Expand Search), _ decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
5 w » 5 wt (Expand Search)
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Ether induces proteotoxic stress, leading to a decrease in Trx protein and an increase in Hsp90 clients that are joint targets of Trx and Ubx.
Published 2024“…<b>(F)</b> Representative images of Acridine Orange-stained <i>yw</i> embryos for the following cases: no treatment (up left), 5-min immersion in Citrasolv solution [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002629#pbio.3002629.ref046" target="_blank">46</a>] (up right), 5-min immersion in ether liquid (bottom right), and 1.5-h exposure to ether vapor (bottom left). …”
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Glial 5-HT<sub>2a</sub> receptors are necessary and rate limiting for experience-dependent synaptic glomeruli pruning.
Published 2024“…The top row is the 5-HT<sub>2A</sub> receptor RNAi control (<i>w</i><sup><i>1118</i></sup><i>; Or42a-mCD8</i>::<i>GFP/+; UAS-5-HT</i><sub><i>2A</i></sub><i>R RNAi/+</i>) with the odorant vehicle (oil, left) and 25% EB exposure (right) from 0–1 dpe showing the experience-dependent innervation pruning. …”
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5-HT2A and Foxo are required in R2/R4 neurons to mediate the effects of death perception on lifespan.
Published 2023“…The following genotypes were used: R2-<i>GAL4</i> x UAS-<i>5-HT2A-RNAi</i> (<i>n</i> = 194 for unexposed and <i>n</i> = 193 for dead-exposed), R2-<i>GAL4</i> x <i>w</i><sup><i>1118</i></sup> (control; <i>n</i> = 191 for unexposed and <i>n</i> = 189 for dead-exposed), R4d-<i>GAL4</i> x UAS-<i>5-HT2A-RNAi</i> (<i>n</i> = 144 for unexposed and <i>n</i> = 134 for dead-exposed), R4d-<i>GAL4</i> x <i>w</i><sup><i>1118</i></sup> (control; <i>n</i> = 148 for unexposed and <i>n</i> = 143 for dead-exposed), R2/R4-<i>GAL4</i> x UAS-<i>5-HT2A-RNAi</i> (<i>n</i> = 182 for unexposed and <i>n</i> = 180 for dead-exposed), and R2/R4-<i>GAL4</i> x <i>w</i><sup><i>1118</i></sup> (control; <i>n</i> = 178 for unexposed and <i>n</i> = 176 for dead-exposed). …”
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Design, Synthesis, and Biological Evaluation of New Peripheral 5HT<sub>2A</sub> Antagonists for Nonalcoholic Fatty Liver Disease
Published 2020“…Here, structural modifications of pimavanserin (CNS drug), a 5HT<sub>2A</sub> antagonist approved for Parkinson’s disease, led us to synthesize new peripherally acting 5HT<sub>2A</sub> antagonists. …”
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Image_3_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg
Published 2021“…Variation in metabolite richness among communities was positively correlated with species richness, but variation in mean chemical similarity was not. Our results are consistent with the hypothesis that plant metabolomes play a more important role in community assembly in wetter and warmer climates, even at temperate latitudes, and suggest that metabolomic traits can provide unique insight to studies of trait-based community assembly.…”
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Image_2_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg
Published 2021“…Variation in metabolite richness among communities was positively correlated with species richness, but variation in mean chemical similarity was not. Our results are consistent with the hypothesis that plant metabolomes play a more important role in community assembly in wetter and warmer climates, even at temperate latitudes, and suggest that metabolomic traits can provide unique insight to studies of trait-based community assembly.…”
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Image_1_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg
Published 2021“…Variation in metabolite richness among communities was positively correlated with species richness, but variation in mean chemical similarity was not. Our results are consistent with the hypothesis that plant metabolomes play a more important role in community assembly in wetter and warmer climates, even at temperate latitudes, and suggest that metabolomic traits can provide unique insight to studies of trait-based community assembly.…”
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Image_4_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg
Published 2021“…Variation in metabolite richness among communities was positively correlated with species richness, but variation in mean chemical similarity was not. Our results are consistent with the hypothesis that plant metabolomes play a more important role in community assembly in wetter and warmer climates, even at temperate latitudes, and suggest that metabolomic traits can provide unique insight to studies of trait-based community assembly.…”
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