Showing 41 - 60 results of 65,915 for search '(((( 5 ht decrease ) OR ( 5 we decrease ))) OR ( 5 ((mean decrease) OR (a decrease)) ))', query time: 0.97s Refine Results
  1. 41
  2. 42
  3. 43
  4. 44

    Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor by Anat Levit Kaplan (12126567)

    Published 2022
    “…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
  5. 45

    Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor by Anat Levit Kaplan (12126567)

    Published 2022
    “…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
  6. 46
  7. 47
  8. 48
  9. 49
  10. 50
  11. 51
  12. 52
  13. 53
  14. 54
  15. 55
  16. 56

    Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV by Henryk Majczyński (830716)

    Published 2020
    “…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT<sub>2</sub> (Cyproheptadine; Cypr), 5-HT<sub>2A</sub> neutral antagonist (Volinanserin; Volin), 5-HT<sub>2C</sub> neutral antagonist (SB 242084), and 5-HT<sub>2B/2C</sub> inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”
  17. 57
  18. 58

    Image5_The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice.JPEG by Vladimir M. Pogorelov (133492)

    Published 2023
    “…Despite these benefits, the hallucinogenic actions of these drugs at the serotonin 2A receptor (5-HT2AR) limit their clinical use in diverse settings. …”
  19. 59
  20. 60