Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

VEEV CPD shows decreased phosphorylation of capsid and replication is not sensitive to loss of PKCδ. by Brian D. Carey (6092747)

Phenotypic delay decreases the probability of a bacterial infection surviving antibiotic treatment. by Martín Carballo-Pacheco (8911910)

Effects of GJE extract treatment decreased accumulation of Col1a1. by Natnicha Suttawong (22367172)

mTORC1 hyperactivation led to a decreased autophagic activity in the podocytes. by Wakiko Iwata (8600457)

“…(<b>B</b>) <i>FIP200</i> and <i>ATG101</i> mRNA expressions were decreased in the primary cultured podocytes from <i>Tsc2</i>^{Δ<i>podocyte</i>}. …”

Juvenile demyelination leads to a decrease in axonal complexity of PFC PV interneurons. by Sara Hijazi (21656615)

“…<b>F</b>. Example image of a biocytin-labeled PFC PV interneuron from a control mouse (left) and from cuprizone-treated mouse (right); scale bar: 50 µm. …”

Skp2 inhibitor SKPin C1 decreased viability and proliferation of multiple myeloma cells and induced apoptosis by Ying Yang (24175)

“…In contrast, 50 μM SKPin C1 only marginally decreased viability of normal B lymphocytes in 12 h. …”

<i>crh-1</i> mutants exhibit a decrease of <i>daf-7</i> expression in the ASI neurons. by JiSoo Park (11133976)

Inverse Phase Transition in Droplet Clusters Levitating over the Locally Heated Water Layer by Alexander A. Fedorets (7376702)

“…Self-assembled microdroplet clusters can levitate above a locally heated water surface. Normally, the temperature of droplets is in the range of 50–95 °C. …”

Inverse Phase Transition in Droplet Clusters Levitating over the Locally Heated Water Layer by Alexander A. Fedorets (7376702)

“…Self-assembled microdroplet clusters can levitate above a locally heated water surface. Normally, the temperature of droplets is in the range of 50–95 °C. …”

Inverse Phase Transition in Droplet Clusters Levitating over the Locally Heated Water Layer by Alexander A. Fedorets (7376702)

“…Self-assembled microdroplet clusters can levitate above a locally heated water surface. Normally, the temperature of droplets is in the range of 50–95 °C. …”

Retinoic acid decreases intracellular K⁺ in pectoral fin buds via transcriptional activation of the calcineurin inhibitor <i>rcan2</i>. by Xiaowen Jiang (8291814)

Proteasomal activity decreases with ApoE4 expression. by Nathan R. Zuniga (20422428)

The decrease or inhibition of Hsp90 induced REST degradation. by Raúl Orozco-Díaz (7067624)

“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …”

Decrease in vRNA in brain during antiretroviral therapy. by Sonny R. Elizaldi (9684796)

Decreased GSH/GSSG redox balance in glaucoma monocytes. by Takeshi Yabana (8201211)

Decrease of autoantibody levels in highly inflammatory NSG mice. by Henrika Jodeleit (4722312)

The ATR-CHK1 inhibitor AZD6738 decreases HBV cccDNA level. by Kaitao Zhao (3617825)

HFD induces LDs and decreases ER and mitochondria in nephrocytes. by Aleksandra Lubojemska (10746241)

“…(<b>C</b>) LDs, stained with a neutral lipid dye (LipidTOX), are more abundant in pericardial nephrocytes (dashed outlines) of HFD than STD larvae. …”

<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays. by Ling Tian (107492)