Showing 121 - 140 results of 34,389 for search '(((( 5 nm decrease ) OR ( 5 point decrease ))) OR ( 5 ((ng decrease) OR (we decrease)) ))', query time: 0.89s Refine Results
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    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

    Published 2022
    “…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
  4. 124

    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

    Published 2022
    “…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
  5. 125

    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors by Mirko Scortichini (4007366)

    Published 2022
    “…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
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    High resolution structures visible with the 25 nm zone plate objective. by Kamal L. Nahas (13014698)

    Published 2022
    “…(<b>F</b>) The width of nuclear capsids was remeasured after imaging with the 25 nm zone plate: 124.5 nm ± 0.96 nm SEM (n = 80 from 4 tomograms; 8.55 nm SD). …”
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