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nm decrease » _ decrease (Expand Search), we decrease (Expand Search), gy decreased (Expand Search)
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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
e point » _ point (Expand Search), 5 point (Expand Search), a point (Expand Search)
5 nm » 5 mm (Expand Search), 5 cm (Expand Search)
point decrease » point increase (Expand Search)
nm decrease » _ decrease (Expand Search), we decrease (Expand Search), gy decreased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
e point » _ point (Expand Search), 5 point (Expand Search), a point (Expand Search)
5 nm » 5 mm (Expand Search), 5 cm (Expand Search)
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Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors
Published 2022“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
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Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors
Published 2022“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
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304
Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors
Published 2022“…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …”
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Cullin-1/5 are required for NF-κB signaling during <i>Eh</i>-macrophage contact.
Published 2021Subjects: -
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Anisotropic Contraction of a Polyaromatic Capsule and Its Cavity-Induced Compression Effect
Published 2020“…The resultant capsule, composed of two metal ions and four <i>ortho</i>-substituted ligands, possesses a spheroidal cavity (1.1 nm × 1.5 nm × 1.5 nm) fully encircled by a polyaromatic framework. …”
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A Bifunctional Three-Dimensional Zn(II) Metal–Organic Framework with Strong Luminescence and Adsorption Cr(VI) Properties
Published 2024“…This <b>3D-Zn-MOF</b> has two different types of pores (4.5 × 4.5 Å<sup>2</sup>, 5.7 × 5.7 Å<sup>2</sup>). …”
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Dysregulated alternative splicing in DM1 hiNeurons at 10 DPI.
Published 2022“…(b) Scatter plots pertaining to Fig 5a show increased inclusion of <i>MBNL</i>1 e5 (top), <i>MBNL</i>2 e5 (bottom left) and <i>MBNL</i>2 e8 (bottom right) in DM1 hiNeurons. …”
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