Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”

Stable isotope biplots of end-members (colored points) faceted by coastscape and overlayed consumers (gray points). by Nathan D. McTigue (10706460)

Pancreatic cancer cell proliferation is decreased upon M344 treatment. by Shelby M. Knoche (13833807)

Image_5_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf by Marta Díaz (337207)

“…Circulating exosomes of SGAs (as compared to those of AGAs) had a larger size at birth [146.8 vs 137.8 nm, respectively; p=0.02], and were in lower number at ages 2 [4.3x10¹¹vs 5.6x10¹¹ particles/mL, respectively; p=0.01] and 7 [6.3x10¹¹vs 6.8x10¹¹ particles/mL, respectively; p=0.006]. …”

Decrease of autoantibody levels in highly inflammatory NSG mice. by Henrika Jodeleit (4722312)

Electrically Controlled Lasing in Supercooled Liquid Crystal Blue Phase I Microdroplets by Gia Petriashvili (8920925)

“…When the electric field intensity is increased, the lasing intensity is increased too along with the linewidth that decreases from 6 to 2.5 nm. Besides, the laser lines were shifted toward the shorter wavelength by 11 nm. …”

Impact of 8-MOP concentration (0 ng/ml, 200 ng/ml, or 300 ng/ml) on cellular response after a 2 J/cm² UVA dose. by Marie Laulhé (6416483)

Detection of oxidized proteins by oxyblot in HL-1 cells exposed for 12 or 72h to LG, NG, HG or IHG. by Patrick Mordel (17020879)

Changes in NT-proBNP, LVEF, E/e’ (FAS), and TRPG (PPS) in each HFrEF and HFpEF patients. by Masashi Sakuma (3923087)

Discovery of Novel Imidazo[4,5‑<i>c</i>]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Inte... by Xuewu Liang (3071676)

“…Especially, lead compound <b>8l</b> showed potent inhibitory activities against interferon-stimulated genes (IC₅₀: 3.3 nM) and NF-κB pathways (IC₅₀: 150.7 nM) and decreased the release of various proinflammatory factors at the nanomolar level, including IL-6, IL-8, IL-1β, TNF-α, IL-12, and IFN-γ. …”

Image 5_Exploration of the diagnostic and prognostic roles of decreased autoantibodies in lung cancer.tif by Ying Ye (72583)

“…Moreover, 5 of the decreased autoantibodies can also be applied for supervising bone metastasis in lung adenocarcinoma. …”

Quantification and accuracy of average VAF. by Lizhi Yu (12476136)

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Analytical sensitivity and reproducibility. by Lizhi Yu (12476136)

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Depth of coverage and heterogeneity of the mutation loci. x-axis, mutation loci in sample set one or two; y-axis, depth of coverage after UMI consolidation. by Lizhi Yu (12476136)

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Schematic overview of the cross-platform study. by Lizhi Yu (12476136)

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Reference mutations versus background noise across replicates. by Lizhi Yu (12476136)

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Coverage of reference gene panel by assay A to E for reference samples. by Lizhi Yu (12476136)

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Impact of mutation type on VAF quantification performance. by Lizhi Yu (12476136)

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