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Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms
Published 2023“…The role of environmental allergens (aeroallergens) in triggering AD remains unclear. ObjectiveWe systematically synthesized evidence regarding the benefits and harms of allergen immunotherapy (AIT) for AD. …”
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Emergency endovascular management of penetrating gunshot injuries to the arteries in the face and neck
Published 2014“…We report our experience with EVT of acute GSIs and review the existing literature. …”
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Methylomic profiling in trisomy 21 identifies cognition- and Alzheimer’s disease-related dysregulation
Published 2019“…</p><h3>Materials and Methods</h3><p dir="ltr">A genome-wide DNA methylation study was performed using Illumina Infinium® MethylationEPIC BeadChips on whole blood DNA of 3 male T21 patients with low IQ, 8 T21 patients with high IQ (4 males and 4 females), and 21 age- and sex-matched control samples (12 males and 9 females) in order to determine whether DNA methylation alterations could help explain variation in cognitive impairment between individuals with T21. In view of the increased risk of developing AD in T21 individuals, we additionally investigated the T21-associated sites in published blood DNA methylation data from the AgeCoDe cohort (German study on Ageing, Cognition, and Dementia). …”
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A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia...
Published 2004“…Novel agents to treat acute myeloid leukemia (AML) are needed with increased efficacy and specificity. We have synthesized a dual-specificity fusion toxin DTU2GMCSF composed of the catalytic and translocation domains of diphtheria toxin (DT) fused to the granulocyte-macrophage colony-stimulating factor (GM-CSF) in which the DT furin cleavage site 163RVRRSV170 is modified to a urokinase plasminogen activator (uPA) cleavage site 163GSGRSA170, termed U2. …”
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Genetic Polymorphism Effect on Warfarin–Rifampin Interaction: A Case Report and Review of Literature
Published 2021“…Genetic polymorphisms determine up to 50% of warfarin dose variability. A 38-year-old woman was started on warfarin and rifampin for cerebral venous sinus thrombosis and pulmonary tuberculosis. …”
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Comparative Effectiveness and Safety of Direct Oral Anticoagulants in Low Body Weight Patients with Atrial Fibrillation: A Systematic Review and Meta-analysis
Published 2024“…DOAC analogs were associated with increased stroke-related events, composite outcome, and mortality in low body weight patients compared to non-low body weight patients (odds ratio [OR] 1.50, 95% confidence interval [CI] 1.17–1.92), (OR 1.55, 95% CI 1.29–1.86), (OR 2.92, 95% CI 1.87–4.58), respectively. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…We assess the effects of stretch rate on the mechanical properties of Prolene® (Ethicon, Gynecare, Somerville, NJ, USA), a knitted polypropylene mesh. …”
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Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity
Published 2023“…Microscopic observation confirmed that Tetraselmis sp. held the small cells inside the flocs using their flagella. Thus, we can conclude that mixing microalgal cells in a specific ratio and at a specific pH increases the recovery efficiency of small-sized microalgae that can be difficult to harvest, such as Picochlorum sp. …”
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Control of breathing by raphe obscurus serotonergic neurons in mice
Published 2011“…We used optogenetics to determine the global respiratory effects produced by selectively stimulating raphe obscurus (RO) serotonergic neurons in anesthetized mice and to test whether these neurons detect changes in the partial pressure of CO2 , and hence function as central respiratory chemoreceptors. …”
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Liver resection for liver metastases from nondigestive endocrine cancer
Published 2012“…However, these reports included various types of malignancies and relatively small sample sizes, which limits the ability to draw strong conclusions regarding patient selection.9, 10, 11 and 12 Given improvements in the efficacy of systemic therapy for endocrine tumors13 and 14 and improvements in the safety of liver resection,15 the number of patients with HNEM who are potential candidates for surgery is increasing. In this study, we evaluated the postoperative and long-term outcomes of patients who underwent liver resection for HNEM. …”
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Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positiv...
Published 2009“…Patients were subdivided into four groups according to ALNR value (<.25, .25–.49, .50–.74, .75–1.00). Study parameters were compared at the univariate and multivariate levels for their effect on OS. …”
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Suboptimal dietary knowledge predicts lower diet quality for cancer prevention among university students in Beirut
Published 2025“…The mean knowledge score was 49.5%. Over 50% of students were aware of the association between red and processed meat, sodium, fruits and vegetables, obesity, and cancer. …”
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Coevolving residues distant from the ligand binding site are involved in GAF domain function
Published 2025“…Mutational incorporation into a Bioluminescence Resonance Energy Transfer (BRET)-based biosensors, which detects ligand-induced conformational changes, showed altered GAF domain conformation and increased EC50 for cGMP-induced conformational changes. …”
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Lifetime prevalence, risk, and treatment of mood and anxiety disorders in Qatar's national mental health study
Published 2024“…</p><h3>Methods</h3><p dir="ltr">We conducted a national phone survey of 5,195 Qatari and Arab residents in Qatar (2019–2022) using the Composite International Diagnostic Interview Version 3.3 and estimated lifetime mood and anxiety defined diagnoses. …”
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Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications
Published 2024“…Additionally, the weight loss during <i>in vitro</i> degradation showed that the presence of Mg had significantly increased the degradation rate of composite samples. …”
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Advances in photothermal catalysts for solar-driven hydrogen production
Published 2024“…By analyzing a range of materials, we summarize key performance metrics, including hydrogen evolution rates ranging from 0.47 mmolh<sup>−1</sup>g<sup>−1</sup> for Ti@TiO<sub>2</sub> to 22.50 mmolh<sup>−1</sup>g<sup>−1</sup> for Mn<sub>0.2</sub>Cd<sub>0.8</sub>S/NiSe<sub>2</sub>. …”
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Ghost-NeRV: Efficient Neural Video Representation via Ghost Convolutions
Published 2026“…Extensive experiments on multiple video sequences demonstrate that Ghost-NeRV achieves up to 50% reduction in GFLOPs and approximately 19% reduction in model size, while maintaining stable reconstruction quality. …”
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