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point decrease » point increase (Expand Search)
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Downregulation of DOM decreases the abundance of PER and TIM.
Published 2019“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”
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mGluR5 receptor decreased glycinergic currents.
Published 2019“…<p>(<b>A–B</b>) Bath perfusion of DHPG for 3 min reduced GlyR-IPSCs (<b>A</b>; 70.2 ± 4.2% of baseline at 15–20 min post-DHPG, <i>t</i>[16] = 6.707, <i>p</i> < 0.001, paired Student <i>t</i> test), but not GABA<sub>A</sub>-receptor–mediated IPSCs (<b>B</b>; 102.9 ± 3.3% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 0.347, <i>p</i> = 0.743) in spinal slices of mice. …”
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Beta-catenin signaling is decreased in intermediate progenitor cells.
Published 2010“…(<b>B</b>) To quantify differences in signaling between Tbr2+ and Tbr2- cells, fluorescence intensity of Tbr2 and GFP was measured in the area over each of the nuclei in the VZ and SVZ (right). Scale bars are 50 µm. * * = P<0.001, t test, two-tailed. (<b>C</b>) To further quantify signaling differences between Tbr2+ and Tbr2- cells, dorsolateral neocortices from E13.5 Eomes::GFP embryos (n = 3) were FACS sorted for GFP+ and GFP- cells (see cartoon). mRNA from these cells was isolated and reverse transcribed into cDNA for real-time PCR analysis. …”
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Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant.
Published 2017“…<p>(A) Lysates from strains in stationary phase (A<sub>600</sub>>5.0) were subjected to native gel electrophoresis followed by an in-gel activity assay with the fluorogenic proteasome substrate Suc-LLVY-AMC. …”
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The 5’SS motif decreases mRNA stability and promotes nuclear retention.
Published 2015“…Note that the relative level of <i>c-ftz-Δi-V5-His</i> decreases over the first 60 min until 40–50% of the mRNA remains, after which point the ratio is stable. …”
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Decreased cell stiffness after dissociation of intercellular adhesion.
Published 2014“…At each interval, we obtained (<b>A</b>) microscopic images (original magnification: 100x), (<b>B</b>) AFM topography images (scan size <b>B1</b>, 50 µm; <b>B2</b>, 20 µm; <b>B3</b>, 33.3 µm), and (<b>C</b>) height measurements at the cross section of an individual cell. …”
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Decreased macrophage recruitment correlates with decreased angiogenesis.
Published 2013“…Scale bars represent 50 µM. Results in each figure panel are representative of a minimum of three different mice for each treatment group and genotype.…”
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Capzb2 coimmunoprecipitates with βIII-tubulin in brain lysates and decreases tubulin polymerization in vitro.
Published 2009“…<p>(A) In order to avoid overlap of the heavy chain signal (∼50 kDa) with the βIII-tubulin signal (∼55 kDa) in the immunoprecipitation using the Capzb2 monoclonal antibody (mAb), the antibody was coupled to the protein G/A beads through cross-linking. βIII-tubulin and Capzb2 signals were each detected following immunoprecipitation from brain lysate with both βIII-tubulin rabbit antibody (rAb)-coupled beads and Capzb2 mAb-coupled beads. …”
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