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261
P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
Published 2010“…The lack of response to treatment in ALS may be, at least in part, due to increased activities of efflux pumps in relation to disease, leading to subtherapeutic brain concentrations of drugs. In the present study, we used a transgenic mouse model of ALS (G86R mSOD1 mice) to test this hypothesis. …”
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262
Drug-free phototherapy of superficial tumors
Published 2021“…After a 9-h exposure in vitro, the viability of Human Malignant Melanoma cells (A375) decreased by around 70%. …”
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263
Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
Published 2017“…Results: The results showed a decrease in the proliferation of U937 after 48hrs with IC50 at 24mg/ml. …”
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264
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…Finally, as a definitive and specific way to modulate SLFN11 expression we implemented SLFN11 dCas9 (dead CRISPR associated protein 9) systems to specifically increase or decrease SLFN11 expression.…”
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Influenza prevalence and vaccine efficacy among diabetic patients in Qatar
Published 2023“…Among the typed IVA-positive cases, 33.4% were H1N1, and 7.7% were H3N2. A significant decrease in influenza infections was reported in vaccinated DM patients (14.5%) when compared to non-vaccinated patients (18.9%) (p-value = 0.006). …”
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Palladin Regulates Invadopodia Formation in Glioblastoma
Published 2021“…The results show an increase in invadopodia as seen by TKS4 and TKS5 staining as well as a decrease in Cdc42 activity following palladin knockdown. …”
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269
Predicting Compression Modes and Split Decisions for HEVC Video Coding Using Machine Learning Techniques
Published 2017Get full text
doctoralThesis -
270
Effect of Acute and Chronic Moderate Red or White Wine Consumption on Fasted and Postprandial Lipemia in the Rat
Published 2006“…Fasted rats, in the acute study, were loaded intragastrically with 5 ml of an olive oil emulsion (30% w/v) in the presence or absence of wine (8% v/v ethanol), and either mesenteric lymph or blood was collected 3 h postprandially. …”
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271
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
Published 2017“…Treatment of HaCaT-ras A5 and HaCaT-ras II4 cells with F2 fraction resulted in the accumulation of cells in the sub-G1 apoptotic phase and decreased the population of cells in the S and G2/M phases. …”
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272
Role of Edge Groups in Defining the Stability of Aromatic Molecules Under Electron Irradiation
Published 2024“…<p dir="ltr">Electron irradiation is known to be an important physical tool in tuning the properties of self-assembled organic molecules. Here, we use X-ray photoelectron spectroscopy (XPS) measurements to study the effect of electron bombardment on the structural properties of dithiol aromatic molecules, where the sulfur atoms are either in direct conjugation with phenyl rings (case of Biphenyl-4,4′-dithiol, BPN) or separated by a methylene group (case of 5,5′-bis(mercaptomethyl)-2,2′-bipyridine, BPD). …”
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Impact of severe hypoglycemia on the heat shock and related protein response
Published 2021“…At baseline, MAPKAPK5 (p = 0.02) and UBE2G2 (p = 0.003) were elevated and STUB1 decreased (p = 0.007) in T2D. …”
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Application of hierarchical oligonucleotide primer extension (HOPE) to assess relative abundances of ammonia- and nitrite-oxidizing bacteria
Published 2017“…In contrast, Nitrosospira remained stable in its relative abundance against the total community throughout the operational phases. There was a corresponding significant decrease in the relative abundance of NOB, specifically Nitrospira and those affiliated to comammox, during the shock loading. …”
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Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes
Published 2005“…Cumulative concentrationresponse curve to the non-selective E-adrenergic agonist isoprenaline (Iso) indicated a 33% decrease of the maximal cAMP accumulation produced by Iso while the effect of the hydrosoluble forskolin analog, L-858051 at a saturating concentration (100 µM) was unchanged between the two groups. …”
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Did the periodic intensification of routine immunisation strategy (Intensified mission Indradhanush) reduce the demand for pediatric antibiotic formulations in India?
Published 2025“…We conducted interrupted time series analyses by fitting a Poisson regression model. …”
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Energy Efficient Refurbishment for Existing Office Building in UAE
Published 2011“…Upon preliminary screening a B+G+5 storey office building built in mid nineties was chosen as base building for the study. …”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Optimized periodic based manual cleaning with between 5.78% to 28.39% improvement. 4. Periodic based automatic cleaning showed decreases in improvement of between 164.64% to 245.34%. …”
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Dispatchable capacity optimization strategy for battery swapping and charging station aggregators to participate in grid operations
Published 2023“…Considering the characteristics of an aggregator’s multilateral services, in this study, BSCSs need to ensure the quality of swapping service for EV users and participate in the demand-side regulation response. Firstly, we analyze the operation mechanism of a BSCS in the aggregation mode and propose a state transition model for EV batteries. …”
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Endocrine contribution to the sexual dysfunction in patients with advanced chronic kidney disease and the role of hyperprolactinemia
Published 2021“…Patients treated with cabergoline (<i>n</i> = 26) showed a significant increase in LH levels (<i>p</i> = .003) and a significant decrease in prolactin levels (<i>p</i> = .003). …”