Search alternatives:
sizes decrease » size increase (Expand Search), scores decreased (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 sizes » _ sizes (Expand Search)
50 nn » 50 ns (Expand Search), 50 ng (Expand Search), 50 n (Expand Search)
sizes decrease » size increase (Expand Search), scores decreased (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 sizes » _ sizes (Expand Search)
50 nn » 50 ns (Expand Search), 50 ng (Expand Search), 50 n (Expand Search)
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Attenuation of spheroid size decrease or MUC5AC increase by hit compounds.
Published 2023“…<p>Final hit compounds (with hit concentration and corresponding target) that <b>A)</b> increased bronchosphere size compared to DMSO + 3% CSE control bronchospheres or <b>B)</b> decreased secreted MUC5AC. …”
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Supplementary Material for: Longitudinal Decrease in Left Ventricular Size with Age: Impact on Mortality and Cardiovascular Hospitalization
Published 2025“…This study investigated clinical characteristics and outcomes associated with longitudinal decreases in LV size in this population. Methods: We analyzed echocardiographic data from 6,232 adults with normal baseline left ventricular end-diastolic diameter (LVEDD), with a mean interval of 4.8 years between baseline and follow-up echocardiograms. …”
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Primary small molecule screen to identify attenuators of CSE-induced decrease in size and increase in MUC5AC.
Published 2023“…Hit compounds at 1 and 10μM concentrations that <b>B)</b> increased spheroid size (swell) or <b>C)</b> decreased MUC5AC staining in the lumen relative to DMSO and CSE 3%-treated bronchospheres. …”
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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