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nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
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5 we » _ we (Expand Search), 5 wt (Expand Search), 5 w (Expand Search)
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Identification of ALDH6A1 as a Potential Molecular Signature in Hepatocellular Carcinoma via Quantitative Profiling of the Mitochondrial Proteome
Published 2020“…Further metabolic mapping of the HCC mitochondrial proteins narrowed our biological characterization to four proteins, namely, ALDH4A1, LRPPRC, ATP5C1, and ALDH6A1. The latter protein, a mitochondrial methylmalonate semialdehyde dehydrogenase (ALDH6A1), was most strongly suppressed in HCC tumor regions (∼10-fold decrease) in contrast to LRPPRC (∼6-fold increase) and was predicted to be present in plasma. …”
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Image_1_Reduced Ca2+ transient amplitudes may signify increased or decreased depolarization depending on the neuromodulatory signaling pathway.PDF
Published 2022“…Like 5-HT, OA reduces somal Ca<sup>2+</sup> transient amplitudes in ASH neurons. …”
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Data_Sheet_1_A Tool for Computation of Changes in Na+, K+, Cl− Channels and Transporters Due to Apoptosis by Data on Cell Ion and Water Content Alteration.ZIP
Published 2019“…The early decrease in [Cl<sup>−</sup>]<sub>i</sub> and cell volume were associated with an ~5-fold increase in chloride channel permeability. …”
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Presentation_1_Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.pdf
Published 2023“…</p>Methods<p>Bronchoalveolar lavage fluid (BALF) was collected from 50 children with CF aged 1, 3 or 5 years. BALF cells were analyzed using flow cytometry. …”
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Differentially expressed genes (DEGs)<sup>a</sup> showing the greatest fold changes from each potato tissue: 10 with greatest increase in expression and 10 with greatest decrease in expression.
Published 2025“…<p>Differentially expressed genes (DEGs)<sup>a</sup> showing the greatest fold changes from each potato tissue: 10 with greatest increase in expression and 10 with greatest decrease in expression.…”
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Data Sheet 5_Phosphodiesterase 7: a potential novel therapeutic target in ovarian cancer.pdf
Published 2025“…</p>Results and discussion<p>MTT assays revealed that while BRL 50481 reduced metabolic cellular viability (MCV) in A2780 (IC50 = 200 μM), its combination with PTX decreased MCV in both lines, reducing PTX IC50 by 103- and 625-fold in A2780 and OVCAR3, respectively. …”
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Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc...
Published 2024“…Mitochondrial uncouplers such as BAM15 increase respiration and energy expenditure and have potential in treating a variety of metabolic diseases. In this study, we disclose the structure–activity relationship profile of 6-substituted [1,2,5]oxadiazolo[3,4-<i>b</i>]pyridin-7-ol derivatives of BAM15. …”
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