The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin... by Chanel Avenant (409756)

“…We measured testosterone by UHPLC-MS/MS and SHBG by immunoassay in matched pairs of serum samples collected at baseline (D0) and at peak serum progestin levels at 25 weeks post initiation (25W) (n = 214–218 pairs). Both contraceptives substantially decreased, from D0 to 25W, the total testosterone [DMPA-IM D0 0.560, 25W 0.423 nmol/L, -24.3% (p < 0.0001); NET-EN D0 0.551, 25W 0.253 nmol/L, -54.1%, (p < 0.0001)], SHBG [DMPA-IM D0 45.0, 25W 32.7 nmol/L, -29.8% (p < 0.0001); NET-EN D0 50.2, 25W 17.6 nmol/L, -65.1% (p < 0.0001)], and calculated free testosterone levels [DMPA-IM D0 6.87, 25W 5.38 pmol/L, -17.2% (p = 0.0371); NET-EN D0 6.00, 25W 3.70, -40.0% (p < 0.0001)]. …”

Intake and digestibility during two digestibility trials (1: 20–28 d; 2: 50–56 d) of dairy calves fed different additives in the starter feed (n = 15). by Luisa F. L. Salazar (6664121)

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Neuronal expression of A53T, E46K, G51D, and H50Q αSyn showed an early decline in locomotor function. by Ryusuke Sakai (2961507)

“…Flies expressing either A53T, E46K, G51D, or H50Q αSyn showed a significant decrease in locomotor function compared with control flies, whereas flies expressing WT αSyn did not. …”

Defects in the conduction of somatosensory evoked potentials of median and tibial nerves in a healthy child and in H-ABC patient. by Jose R. Eguibar (8563227)

Comparison of 6 virtues between the two groups [PCOS (n = 49); non-PCOS (n = 50)]. by Ghina Ghazeeri (766076)

Temperature-sensitive germline immortality exhibit decreased histone methylation. by Katherine Kretovich Billmyre (6524396)

Population behavior of split drive components <i>Rescue</i>^<i>tko</i> and Cas9/<i>Cleaver</i> alone and together as a complete split^50cM <i>ClvR</i> V2 elemen... by Georg Oberhofer (3401438)

PRV-induced infertility is caused by decreased P4 level. by Bing-Qian Su (8616981)

Decreased expression of V-ATPase upon the siRNA transfection. by Manisha Naskar (2613763)

Submandibular gland removal decreases avoidance of bitter taste in mice by Masataka Narukawa (20599511)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…(<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …”

Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>. by Naoto Haruyama (487384)

“…Compared with the co-culture of WT BMCs and WT calvarial cells (WT / WT), the number of osteoclasts were significantly decreased at 50% in the co-cultures of TgLRAP BMCs and TgLRAP calvarial cells (TgLRAP / TgLRAP) (graph). …”

Heart specific RNase Z variants show a mild decrease in longevity and locomotor response. by Ekaterina Migunova (15909887)

Binding of C4BP decreases the association of CEACAM-binding Opa+ <i>N</i>. <i>gonorrhoeae</i> with neutrophils. by Lacie M. Werner (14710419)

m 6A RNA Methylation Decreases Atherosclerotic Vulnerable Plaque Through Inducing T Cells by Chunmei Qi (739294)

“…<div><p>ABSTRACT Introduction: Knockdown of fat mass and obesity-associated gene (FTO) can induce N6-methyladenosine (m 6A) ribonucleic acid (RNA) methylation. …”

Fig 2 - by Chadapust J. Sudsiri (14670602)

“…The Tukey test interval for testing for significant (p < 0.05) differences between any two mean cell volume values (Fig 2A) was V_c = 9.50 μm³: V_c at the two temperature were not significantly different but at [Na⁺] above the control concentration (148 mM) there was significant decreases in cell volume. …”

No change in muscle size and force, but a decrease in TB mass in 1-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) by Ariel L. Burgio (15069256)

“…Our studies revealed <b>SLB1122168</b> (<b>33p</b>), which is a potent inhibitor (IC₅₀ = 94 ± 6 nM) of Spns2-mediated S1P release. …”

Nanodomains and Their Temperature Dependence in a Phosphonium-Based Ionic Liquid: A Single-Molecule Tracking Study by Jemima Opare-Addo (14657955)

Subjects: