Search alternatives:
wt decrease » we decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
n decrease » nn decrease (Expand Search), a decrease (Expand Search), _ decreased (Expand Search)
_ decrease » _ decreased (Expand Search)
5 wt » _ wt (Expand Search), 5 ht (Expand Search)
2 wt » _ wt (Expand Search), i wt (Expand Search), 2 w (Expand Search)
wt decrease » we decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
n decrease » nn decrease (Expand Search), a decrease (Expand Search), _ decreased (Expand Search)
_ decrease » _ decreased (Expand Search)
5 wt » _ wt (Expand Search), 5 ht (Expand Search)
2 wt » _ wt (Expand Search), i wt (Expand Search), 2 w (Expand Search)
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The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties.
Published 2020“…<i>n</i> = 4 oocytes for WT (pH IC<sub>50</sub> = 7.49 ± 0.016) and 5 oocytes for C456Y (pH IC<sub>50</sub> = 7.11 ± 0.0075), *<i>P</i> = 0.016, Mann-Whitney. …”
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WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression.
Published 2024“…Corresponding densitometry analysis is noted as protein fold expression compared to GAPDH for WT1, p<0.001(***), vFLIP(ns), LANA p<0.05(*), pAKT p<0.05(*), and BCL2 p <0.05(*) using two-sided, unpaired student t-tests. …”
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NatB inactivation decreased the level of MAPK and proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways.
Published 2020“…In contrast, low NatB activity and low Ac-CoA levels will reduce the levels of Nt-acetylated Grb2/Drk, MAPK, and PP2AC, leading to reduced EGFR signaling due to decreased levels of Grb2/Drk and MAPK (positive components of the pathway) and increased levels of PP2AC (negative component of the pathway). …”
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NatB-inactivation decreased Drk levels through its N-terminal sequences, which was regulated by the N-end rule E3 ubiquitin ligase POE/UBR4.
Published 2020“…In contrast, Ubr1 RNAi (G) or Ubr5 RNAi (H) clones did not affect Drk levels. Ubr4/POE RNAi restored the Drk level in <i>psid-D1</i> clones (I) but did not influence the level of PP2AC (J), suggesting a specific effect of Ubr4 on Drk but not PP2AC degradation.…”
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