50 WT 5′ and 3′ terminal nts of the S1 gene are sufficient to package a non-MRV gene into infectious virions. by Debarpan Dhar (724473)

The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties. by Wangyong Shin (6793040)

“…<i>n</i> = 73 oocytes for WT (5.70 ± 0.61 μA) and 59 oocytes for C456Y (0.039 ± 0.004 μA), ***<i>P</i> < 0.001, Mann-Whitney. …”

Ifit2 deficiency results in decreased neuroinflammation upon RSA59 infection. by Jayasri Das Sarma (652473)

rHSP60 decreases LPS-induced mononuclear cell proliferation. by Igor Emiliano L. Souza (18196495)

Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production. by Bei Wang (116772)

VPS34 inhibition decreases intracellular levels of cholesteryl-esters, blocks cholesterol uptake and enhances lysosomal degradation of LDLR. by Marek J. Kobylarz (9292599)

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”

Titanate Nanosheets/Cellulose Composite Showing Improved Crystallinity and Decreased Water Wettability by Gamma-Irradiation by Yaowaluk Tariwong (22630109)

LuxR G37V has decreased DNA-binding activity. by Chelsea A. Simpson (9579303)

Downregulation of DOM decreases the abundance of PER and TIM. by Zhenxing Liu (399809)

“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Host population bottlenecks decrease microbiome diversity. by Michael Ørsted (5926028)

Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

STAT6-driven immunity decreases <i>N</i>. <i>brasiliensis</i> reproductive output and survival within host. by Annabel A. Ferguson (17616286)

H2-K^b overexpression decreases NSPC proliferation and impairs adult hippocampal neurogenesis. by Karin Lin (11037548)

Cells expressing nsP2 inefficiently present antigen and have decreased levels of cell surface MHC-I. by Brian C. Ware (8544672)

Representative TUNEL- and DAPI-stained sections from the abdominal aortas of young and old WT and smcKlf5^−/− mice following 28 days of Ang II infusion. by Dong Ma (584680)

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

Clustering of metastable states using the first 50 ns of post-translational folding trajectories of CAT-III with ligand bound. by Yang Jiang (46459)

Passive transfer of humanized anti-NS1 mAb 33D2 into DENV-inoculated mice decreases viral titer and NS1 level in mouse sera. by Sen-Mao Tien (12481273)