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point decrease » point increase (Expand Search)
026 decrease » _ decrease (Expand Search), nn decrease (Expand Search)
ht decrease » _ decrease (Expand Search), nn decrease (Expand Search), we decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 point » _ point (Expand Search)
5 ht » 5 h (Expand Search)
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<i>MMP-1</i> OE restores <i>5HT</i><sub><i>2A</i></sub><i>R</i>-deficient experience-dependent pruning.
Published 2025“…<p><b>A</b>, Or42a OSN innervation of VM7 glomeruli shown as a color-coded Z-stack (scale, top right) with 24-hour exposure from 0 to 1 dpe to the mineral oil vehicle control (<u>left</u>) and EB odorant (<u>right</u>) in astrocyte-like glia control (<u>top</u>: <i>w</i><sup><i>1118</i></sup>;<i> Or42a-mCD8::GFP/+; GMR86E01-Gal4/+</i>), the astrocyte-like glia <i>5-HT</i><sub><i>2A</i></sub><i>R</i> RNAi alone (<u>middle</u>: <i>w</i><sup><i>1118</i></sup>;<i>Or42a-mCD8::GFP/+; GMR86E01-Gal4/UAS-5-HT</i><sub><i>2A</i></sub><i>R RNAi</i>), and with <i>MMP-1</i> overexpression (<u>bottom</u>: <i>w</i><sup><i>1118</i></sup>;<i>Or42a-mCD8::GFP/UAS-MMP1; GMR86E01-Gal4/UAS-5-HT</i><sub><i>2A</i></sub><i>R RNAi</i>). …”
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Chemokines, with the exception of CXCL1 and MCP-1, decrease acutely following 5 Gy IR.
Published 2024Subjects: -
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis.
Published 2021“…(<b>H</b>) Quantification of autoradiography for labeled TAG was by ImageJ. <i>n =</i> 5, data are mean ± SD. *<i>p</i> < 0.05. Uncropped western blots are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s016" target="_blank">S1 Raw Images</a>, and numerical data for all graphs are provided in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000988#pbio.3000988.s014" target="_blank">S6 Data</a>. …”
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Analysis of tumour vasculature with the addition of more HT groups.
Published 2020“…The vasculature becomes less evident in the treated groups, with decreasing numbers of stained blood vessels. Images were taken at a 20x objective lens, and the scale bar denotes ~50μm. …”
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