Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We investigated protein glycation and oxidative damage in skeletal muscle of mice with UCP1 expression under control of the human skeletal actin promoter (HSA-mUCP1) at age 12 weeks (young) and 70 weeks (aged). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We investigated protein glycation and oxidative damage in skeletal muscle of mice with UCP1 expression under control of the human skeletal actin promoter (HSA-mUCP1) at age 12 weeks (young) and 70 weeks (aged). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center حسب Hammad Y.A.

"…The transport time significantly decreased from an initial majority of > 15 mins duration, to a majority of < 15 mins transport time after the second audit; there was a 50% improvement in 30 mins response time; and the percentage of requests processed in < 10 mins were significantly higher after the second audit. …"
احصل على النص الكامل

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Ganji, Vijay

احصل على النص الكامل
احصل على النص الكامل

Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
احصل على النص الكامل
احصل على النص الكامل

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach حسب P., Sneha

"…Second, the sequence conservation and DNA-binding sites of the mutant positions were assessed; as HNF1A protein is a transcription factor. …"
احصل على النص الكامل
احصل على النص الكامل

Oral PTCTS (Particulated Transialidase) Removes Serum Microparticles and Decreases Inflammation in Atherosclerotic Plaques of Rabbits حسب Garavelo, Sherrira M.

احصل على النص الكامل
احصل على النص الكامل

A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase حسب Thirumal Kumar, D

"…Considering true positives, true negatives, false positives, and false negatives, three mutations (Y114E, R128G, and C145A) showed "loss of DNA repair activity," and were analyzed further using molecular dynamics simulations (MDS) using GROMACS for 50ns. …"
احصل على النص الكامل
احصل على النص الكامل

Biophysical studies of the effect of high power ultrasound on the DNA solution حسب Ali, Mohamed H.M.

"…The decrease in the dielectric increment indicated a decrease in length of DNA molecule after exposure to ultrasound power.…"
احصل على النص الكامل
احصل على النص الكامل

Biocorrosion behavior of biodegradable nanocomposite fibers coated layer-by-layer on AM50 magnesium implant حسب Abdal-hay, Abdalla

"…The results showed that the AJS 3D membrane fiber layers, particularly the hybrid membrane layers containing a small amount of nHA (3wt.%), induce a higher biocorrosion resistance and effectively decrease the initial degradation rate compared with the neat AM50 coupon samples. …"
احصل على النص الكامل
احصل على النص الكامل

The mitochondrial-related effect of the 905 nm photobiomodulation therapy on 50B11 sensory neurons حسب Zupin, Luisa

"…In this study, a possible molecular mechanism of the 905 nm PBMT (0.25 W/cm2; 3, 6, 12, and 18 J/cm2, 5 Hz) analgesic effect was tested on 50B11 cells, by investigating its impact on mitochondria. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Effect of Visual Impairment and Its Severity on Vision-Related and Health-Related Quality of Life in Jordan: A Comparative Cross-Sectional Study حسب Jammal, Hisham M.

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Decreasing the use of edible oils in China using WeChat and theories of behavior change: study protocol for a randomized controlled trial. حسب Zhu, Rui

احصل على النص الكامل
احصل على النص الكامل

Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model. حسب Al-Kandari, Halema

احصل على النص الكامل
احصل على النص الكامل

Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach. حسب Thirumal Kumar, D

"…The DNA repair system is crucial to repair the error resulting in DNA replication. …"
احصل على النص الكامل
احصل على النص الكامل

Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives حسب Zeiz, Ali

"…Results: Compound 1 bearing a chlorine substituent displayed the highest cytotoxic activity against HCT-116 and MCF-7 cancer cells where IC50 values of 49.35 ± 2.685 and 69.32 ± 3.186 µM, respectively, were achieved. …"
احصل على النص الكامل
احصل على النص الكامل

EdgeHealth: An Energy-Efficient Edge-based Remote mHealth Monitoring System حسب Emam A.

احصل على النص الكامل
احصل على النص الكامل

Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salloum-Asfar, Salam

"…From each fibroblast (N = 4), three iPSC clones were examined (N = 12). iPSCs and original fibroblasts expressed miRNA clusters differently and miRNA clusters were compared to mRNA hits. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs حسب Shalaby, Raed

"…The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. …"
احصل على النص الكامل
احصل على النص الكامل

In vitro effects of photobiomodulation therapy on 50B11 sensory neurons: evaluation of cell metabolism, oxidative stress, mitochondrial membrane potential (MMP), and capsaicin-indu... حسب Zupin, Luisa

"…Calcium peak stimulated by capsaicin, the ligand of TRPV1 channel, was decreased in neurons pre-irradiated with the combination of the two wavelengths. …"
احصل على النص الكامل
احصل على النص الكامل