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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes.
Published 2021“…Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”
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Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center
Published 2018“…The transport time significantly decreased from an initial majority of > 15 mins duration, to a majority of < 15 mins transport time after the second audit; there was a 50% improvement in 30 mins response time; and the percentage of requests processed in < 10 mins were significantly higher after the second audit. …”
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Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
Published 2018“…It is classified into three categories: D-2-HGA, L-2-HGA, and combined D,L-2-HGA. The D-2-HGA includes two subtypes: type I and type II caused by the mutations in D2HGDH and IDH2 proteins, respectively. …”
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
Published 2019“…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …”
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Tailoring the deposition of MoSe2 on TiO2 nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting
Published 2023“…In particular, the sample synthesized by sputtering of MoSe2 for 90 s, i.e., MoSe2@TiO2-90 s, depicted the highest current density (1.86 mA cm−2 at 0.5 V vs. …”
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Comparative Study on Gas-Sensing Properties of 2D (MoS2, WS2)/PANI Nanocomposites-Based Sensor
Published 2022“…In this study, we proposed a new design of an NH3 gas sensor that was comprised of two-dimensional (TMDs, mainly WS2 and MoS2) and PANI. …”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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In vitro effects of photobiomodulation therapy on 50B11 sensory neurons: evaluation of cell metabolism, oxidative stress, mitochondrial membrane potential (MMP), and capsaicin-indu...
Published 2021“…Calcium peak stimulated by capsaicin, the ligand of TRPV1 channel, was decreased in neurons pre-irradiated with the combination of the two wavelengths. …”
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Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production
Published 2021“…Hypothesizing that there may be a biochemical link between the two, we examined the potential cross talks of signaling pathways between NKG2D and RKIP. …”
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Allergenicity of roasted peanuts treated with a non-human digestive protease
Published 2015“…Results indicate that alcalase digestion of sonicated peanuts significantly increased protein solubility while decreasing Ara h 1 and Ara h 2 concentrations in both soluble and insoluble portions of peanuts relative to untreated peanuts. …”
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Study of the Ion Interclation Mechanism in Mxene Membrane for the Water Treatment Applications
Published 2020“…Chapter one consists of the introduction and literature review, which provides an overview of the current conventional technology in water treatment applications and how the two-dimensional nanomaterial can improve it. The high water flow of 2D membrane stems from the well-defined nanometer channels that exhibit low friction for the water flow making high water flux membranes. …”
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Association between Serum Vitamin D Status and Circadian Syndrome: A Cross-Sectional Study
Published 2024“…Results: Our results indicated that low vitamin D levels exhibited meaningful associations with CircS, with vitamin D deficiency and inadequacy demonstrating 2.21-fold (95% CI 1.78-2.74, p < 0.001) and 1.33-fold (95% CI 1.14-1.54, p < 0.001) increases in CircS odds, respectively. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
Published 2019“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Biocorrosion behavior of biodegradable nanocomposite fibers coated layer-by-layer on AM50 magnesium implant
Published 2016“…The results showed that the AJS 3D membrane fiber layers, particularly the hybrid membrane layers containing a small amount of nHA (3wt.%), induce a higher biocorrosion resistance and effectively decrease the initial degradation rate compared with the neat AM50 coupon samples. …”
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