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The rate of lariat formation is decreased two-fold by isoginkgetin treatment.
Published 2014“…The indicated values are from an average of three biological replicates, and <i>p</i>-values are from two-tailed <i>t</i>-tests based on mean values for aggregated introns 2–10 (n = 9). …”
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Resveratrol decreases PKM2 expression.
Published 2013“…<p>Resveratrol treatment decreases PKM2 mRNA in (A), HeLa; (B), HepG2 and (C), MCF-7; by approximately two-folds. β-actin was taken as endogenous control and normalized to PKM2 mRNA. …”
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FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells.
Published 2019“…<p>(A) Following 24 hours of treatment with FTY720, the viability of HuH6 cells measured using the alamarBlue cell viability assay was significantly decreased (LD<sub>50</sub> = 8.4 μM, p ≤ 0.05). …”
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Comparison of mean differences in temperature decreases.
Published 2022“…<p>Patients are grouped according to receiving either dipyrone (blue; n = 341) or acetaminophen (red; n = 71) versus patients receiving no antipyretic treatment (n = 315). Graphs display mean differences in temperature decreases between each two comparators (no medication versus dipyrone, no medication versus acetaminophen and dipyrone versus acetaminophen) with their respective 95% confidence intervals. …”
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<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays.
Published 2021“…Significant differences in the chimerism of SLAM cells compared to whole BM were found in KO-F mice (55.2-fold increase in CD45.2<sup>+</sup> KO-F SLAM cells as compared to CD45.2<sup>+</sup> cells in the whole BM, p = 0.0163) and KO-M mice (11.31-fold increase in CD45.2<sup>+</sup> KO-M SLAM cells as compared to CD45.2<sup>+</sup> cells in the whole BM, p = 0.0010). …”
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Transaldolase deficiency causes a starvation-like response that decreases animal fat content and rewires lipid metabolism gene expression.
Published 2017“…<b>(G)</b> Gene expression of starvation-responsive lipid metabolism genes is altered in <i>tald-1(RNAi)</i> animals. Log2 fold change calculated to emphasize the increases and decreases in gene expression levels from RNAi treatments (N = 6–8 independent experiments, error bars indicate s.e.m., paired student’s t-tests with Bonferroni’s correction). …”
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Imetelstat increases FLU-induced γH2AX and decreases FLU-induced pDNA-PK.
Published 2013“…<p>A) The graph represents the mean levels of γH2AX (phosphorylated H2AX) (y-axis) after treatment of CLL lymphocytes as indicated (x-axis) in eight samples. …”
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