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TMD residues decrease sensitivity.
Published 2017“…Glu residues are color coded based upon effect, with residues in red producing a significant decrease in pH<sub>50</sub>, and in yellow, an insignificant or weak effect, whereas the dark purple and magenta for His residues are synonymous to the red of Glu residues. …”
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Resveratrol decreases PKM2 expression.
Published 2013“…<p>Resveratrol treatment decreases PKM2 mRNA in (A), HeLa; (B), HepG2 and (C), MCF-7; by approximately two-folds. β-actin was taken as endogenous control and normalized to PKM2 mRNA. …”
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The rate of lariat formation is decreased two-fold by isoginkgetin treatment.
Published 2014“…<p>(<b>A</b>) Genome-wide expression of 5′ splice sites, 3′ splice sites, and introns are increased relative to exons upon treatment of HeLa cells with isoginkgetin (30 µM, 18 hours), based on total RNA-Seq (dUTP method <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089673#pone.0089673-Parkhomchuk1" target="_blank">[18]</a>, Illumina). …”
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Receptor specific silencing decreases NGF induced apoptosis.
Published 2013“…A 37.5%-decrease (*) and a 50%-decrease (**) of apoptotic signal were detected respectively in p75<sup>NTR</sup>-siRNA and p75<sup>NTR</sup>/trkA<sup>NGFR</sup>-siRNA (p<.05).…”
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Decreased macrophage recruitment correlates with decreased angiogenesis.
Published 2013“…Arrows indicate VWF-positive structures. Scale bars represent 50 µM. Results in each figure panel are representative of a minimum of three different mice for each treatment group and genotype.…”
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