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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center
Published 2018“…The transport time significantly decreased from an initial majority of > 15 mins duration, to a majority of < 15 mins transport time after the second audit; there was a 50% improvement in 30 mins response time; and the percentage of requests processed in < 10 mins were significantly higher after the second audit. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes.
Published 2021“…Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”
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Inner sphere oxidation of N,N′-ethylenebis(isonitrosoacetyleacetoneimine)copper(II) by N-bromosuccinimide in aqueous weakly acidic solutions
Published 2013“…The kinetics of oxidation of N,N'-ethylenebis(isonitrosoacetyleacetoneimine) copper(II) complex, CuL, by N-bromosuccinimide (SBr) in weakly aqueous acidic solutions was studied under pseudo-first-order conditions. …”
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Development of novel blend poly (Ethylene Glycol) / Poly(Ethersulfone) polymeric membrane using N-Methyl-2-Pyrollidone and dimethylformamide solvents for facilitating CO2/N2gas sep...
Published 2020“…On that regard, the enhanced CO2/N2 gas separation performance of the PEG/PES blend membrane can potentially have an important contribution to CO2 separation processes in the industry in order to decrease emissions and minimize the risk of climate change.…”
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CO2 Absorption Capacity and its Enthalpy of Absorption in Aqueous Blend of MDEA/Piperazine/Arginine
Published 2020“…In this work, the solubility data of CO2 in aqueous blends of N-Methyldiethanolamine, Piperazine and Arginine (MDEA/PZ/ARG) of a total concentration of two moles is presented. …”
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In vitro effects of photobiomodulation therapy on 50B11 sensory neurons: evaluation of cell metabolism, oxidative stress, mitochondrial membrane potential (MMP), and capsaicin-indu...
Published 2021“…Calcium peak stimulated by capsaicin, the ligand of TRPV1 channel, was decreased in neurons pre-irradiated with the combination of the two wavelengths. …”
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Advanced Hard Ctings: Towards A Whole New World
Published 2014“…METHODS: Three different thin hard nitrogen-rich coatings were mechanically, microstructurally, and thermally characterized: (i) a 2.5 micron-thick nano-layered CrN-NbN, (ii) a 11.7 micron-thick monolayer TiAlN, and (iii) a 2.92 micron-thick multilayer AlTiCrxNy. …”
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NOVEL HIGHLY ANTIBACTERIAL CORROSION RESISTANT NIP-CEO2-C3N4 NANO-COMPOSITE COATINGS
Published 2024“…The antibacterial assessments conducted on various coating samples, targeting both S. aureus and E. coli bacterial strains, revealed additional improvements with the inclusion of g-C3N4, particularly pronounced when combined with g-C3N4/CeO2, when compared to the blank NiP.…”
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A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
Published 2019“…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …”
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Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
Published 2019“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”
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Biocorrosion behavior of biodegradable nanocomposite fibers coated layer-by-layer on AM50 magnesium implant
Published 2016“…The results showed that the AJS 3D membrane fiber layers, particularly the hybrid membrane layers containing a small amount of nHA (3wt.%), induce a higher biocorrosion resistance and effectively decrease the initial degradation rate compared with the neat AM50 coupon samples. …”
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Acute and chronic toxicity assessments of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2) on the calanoid copepod Acartia clausi: Effects on survival, development, sex-ratio and...
Published 2022“…Copepods showed stage-specific responses against E2 and EE2 acute exposure. The most resistant life stage was N1 with LC50 values > 1500 μg L-1 and >5000 μg L-1, respectively for E2 and EE2. …”
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