Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB Inhibitor by Beatrice Noce (16540800)

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Image1_Phytochemical and toxicological evaluation of Zephyranthes citrina.JPEG by Muhammad Haseeb Ur Rehman (13848379)

“…Uric acid was raised at a dose of 100 mg/kg. In acute toxicity, at 2000 mg/kg, creatinine and uric acid increased while urea levels decreased. …”

Peak stress decreases following a ramp-stretch as the time of stretch (post-load clamp) increases, consistent with the twitch relaxation throughout diastole. by Bertrand C. W. Tanner (18098420)

S1 Fig - by Asadollahi Parisa (8837432)

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S1 Raw images - by Asadollahi Parisa (8837432)

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Macroscopic and histological assessment of colic tumor and inflammation in mice. by Asadollahi Parisa (8837432)

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Flow cytometry analysis of cancer LS174T and normal IEC-18 cells before and after 120h treatment with bifidobacteria cocktail (100 bacteria/cell), cetuximab and trastuzumab. by Asadollahi Parisa (8837432)

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Definitions of the features selected [50]. by Yu Zhang (12946)

Half-maximal inhibitory concentration (IC₅₀), half-maximal cytotoxic concentration (CC₅₀), and selectivity index (SI) of CTLL formulation and its ingredients. by Prapaporn Chaniad (9761710)

Half-maximal inhibitory concentration (IC₅₀), half-maximal cytotoxic concentration (CC₅₀), and selectivity index (SI) of PSCD formulation and its ingredients. by Prapaporn Chaniad (9761710)

Responses to asynchronous pulses of the control, LN, NSI and mix model, similar to Fig 8 but for a short synaptic time scale <i>τ</i>_<i>LN</i> = 25<i>ms</i>. by Mario Pannunzi (553941)

Genetic progress for FFB (in percentage of hybrids performance at generation 0) in the La Mé population according to breeding scheme (RRS with 120 candidates, RRGS with 120 candida... by Billy Tchounke (16965084)

Illustrations of the F1-unseen vs. F1-seen correlations of the SeqFold2D-960K model. by Xiangyun Qiu (316117)

Supplemental Table 1 Kinase Inhibitor Screen from Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Aden... by Brittany L. Allen-Petersen (14935217)

Pairwise correlations in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

HE staining results of lung tissue of guinea pigs in each group (×200,scale = 50μm). by Fangwei Xu (11845586)

Table 1_A novel α-conotoxin [D1G, ΔQ14] LvIC decreased mouse locomotor activity.xls by Wen Wang (6570)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…The antiproliferative activity of the novel <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives was studied against three cancer cell lines, namely, MCF-7, HCT-116, and HepG2. <i>N</i>-(4-Bromophenyl)-4-(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine <b>4f</b>, <i>N</i>-(4-chlorophenyl)-4,6-bis­(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-1,3,5-triazin-2-amine <b>5c</b>, and 4,6-<i>bis</i>(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-<i>N</i>-(4-methoxyphenyl)-1,3,5-triazin-2-amine <b>5d</b> showed promising activity against these cancer cells: <b>4f</b> [(IC₅₀ = 4.53 ± 0.30 μM (MCF-7); 0.50 ± 0.080 μM (HCT-116); and 3.01 ± 0.49 μM (HepG2)]; <b>5d</b> [(IC₅₀ = 3.66 ± 0.96 μM (HCT-116); and 5.42 ± 0.82 μM (HepG2)]; and <b>5c</b> [(IC₅₀ = 2.29 ± 0.92 μM (MCF-7)]. …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…The antiproliferative activity of the novel <i>mono</i>- and <i>bis</i>(dimethylpyrazolyl)-<i>s</i>-triazine derivatives was studied against three cancer cell lines, namely, MCF-7, HCT-116, and HepG2. <i>N</i>-(4-Bromophenyl)-4-(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine <b>4f</b>, <i>N</i>-(4-chlorophenyl)-4,6-bis­(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-1,3,5-triazin-2-amine <b>5c</b>, and 4,6-<i>bis</i>(3,5-dimethyl-1<i>H</i>-pyrazol-1-yl)-<i>N</i>-(4-methoxyphenyl)-1,3,5-triazin-2-amine <b>5d</b> showed promising activity against these cancer cells: <b>4f</b> [(IC₅₀ = 4.53 ± 0.30 μM (MCF-7); 0.50 ± 0.080 μM (HCT-116); and 3.01 ± 0.49 μM (HepG2)]; <b>5d</b> [(IC₅₀ = 3.66 ± 0.96 μM (HCT-116); and 5.42 ± 0.82 μM (HepG2)]; and <b>5c</b> [(IC₅₀ = 2.29 ± 0.92 μM (MCF-7)]. …”

Corn gluten meal induces enteritis and decreases intestinal immunity and antioxidant capacity in turbot (<i>Scophthalmus maximus</i>) at high supplementation levels - Fig 2 by Nan Bai (1576645)

“…</b> (a–d) Representative images of decreased height and increased fusion of the mucosal folds with increasing corn gluten meal level (bar = 500 <b>μ</b>m). …”