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DnaK’s ATPase activity is stimulated by ribosomes and required to reduce protein synthesis.
Published 2024Subjects: -
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TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Diabetic kidney shows decreased klotho expression.
Published 2021“…<p>(a) Representative images of the kidney from normal and diabetic biopsies showing the decreased klotho expression in diabetic podocytes by IHC. …”
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mTORC1 hyperactivation led to a decreased autophagic activity in the podocytes.
Published 2020“…(<b>B</b>) <i>FIP200</i> and <i>ATG101</i> mRNA expressions were decreased in the primary cultured podocytes from <i>Tsc2</i><sup>Δ<i>podocyte</i></sup>. …”
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5-fold cross-validation comparison results.
Published 2025“…The experimental results show that the model before pruning has 96.1% and 53.2% mean average precision mAP50 and mAP50:95, respectively, which are 11.9% and 11.1% higher than the original YOLO11n, and the model after pruning also has 10.8% and 9.3% higher than the original YOLO11n, respectively, and the number of parameters is reduced to 279,778, and model size is reduced to 1.3MB. …”
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