The difference in average sensitivities between the inside and outside of CVH (⊿RSo-i) in eyes with CNV (CNV+, n = 6) or without CNV (CNV−, n = 6). حسب Rion Ozawa (13155216)

An Allosteric Modulator of RNA Binding Targeting the N‑Terminal Domain of TDP-43 Yields Neuroprotective Properties حسب Niloufar Mollasalehi (9511076)

"…<i>In silico</i> docking of 50K compounds to the NTD domain of TDP-43 identified a small molecule (nTRD22) that is bound to the N-terminal domain. …"

Analysis of change in mature INPs, GMCs and neurons in the type II NB lineage on depletion of mitochondrial morphology proteins. حسب Dnyanesh Dubal (12085942)

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma حسب Zhihao Liu (419349)

"…In our previous study, we have identified a series of type I PRMT inhibitors, among which ZL-28-6 (<b>6</b>) exhibited increased activity against CARM1 while displaying decreased potency against other type I PRMTs. …"

N1-specific anti-serum decreases replication of A(H1N1)pdm09 in HAE cells. حسب Anouk Smet (713884)

Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer حسب Fan-Fan Shang (16953264)

"…Derivative <b>A11</b> directly binds to the insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) protein with a <i>K</i>_D value of 2.88 nM, which is about 23-fold more potent than CuB, leading to the decreased expression of downstream apoptosis- and cell cycle-related proteins. …"

Notch signaling regulates fused mitochondrial morphology in INPs and muscle cells. حسب Dnyanesh Dubal (12085942)

Step-wise evolution of drug resistance via CNV and LOH. حسب Pétra Vande Zande (17628246)

Self-confidence for LIO-ROP after each step of training (score 0–4). حسب Narisa Rattanalert (21445983)

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) حسب Ariel L. Burgio (15069256)

"…Our studies revealed <b>SLB1122168</b> (<b>33p</b>), which is a potent inhibitor (IC₅₀ = 94 ± 6 nM) of Spns2-mediated S1P release. …"

Design and Synthesis of Novel Spiro Derivatives as Potent and Reversible Monoacylglycerol Lipase (MAGL) Inhibitors: Bioisosteric Transformation from 3‑Oxo-3,4-dihydro‑2<i>H</i>‑ben... حسب Shuhei Ikeda (2380180)

"…Optimization of the left hand side afforded <b>4f</b> as a promising reversible MAGL inhibitor, which showed potent in vitro MAGL inhibitory activity (IC₅₀ 6.2 nM), good oral absorption, blood–brain barrier penetration, and significant pharmacodynamic changes (2-arachidonoylglycerol increase and arachidonic acid decrease) at 0.3–10 mg/kg, po. in mice.…"

Fig 5 - حسب David Mathar (9707947)

S5 Fig - حسب David Mathar (9707947)

E₅₀ values. حسب Junxia Zhou (14381598)

Tube formation: Representative light microscopic images of the structures formed by HPAEC and CTEPH-EC seeded and incubated for 5h30 min in the absence or presence of 50 uM VER-155... حسب William Salibe-Filho (9727738)

Top 50 up-regulated genes in <i>lin-15B(n744</i>), mutant in starved L1 animals. حسب Ashwin Seetharaman (615458)

Modeling methods of included studies (n = 61). حسب Natalie Riva Smith (13899600)

DataSheet_1_Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat.pdf حسب Marta Díaz (337207)