Trial profile. حسب Chanel Avenant (409756)

"…We measured testosterone by UHPLC-MS/MS and SHBG by immunoassay in matched pairs of serum samples collected at baseline (D0) and at peak serum progestin levels at 25 weeks post initiation (25W) (n = 214–218 pairs). Both contraceptives substantially decreased, from D0 to 25W, the total testosterone [DMPA-IM D0 0.560, 25W 0.423 nmol/L, -24.3% (p < 0.0001); NET-EN D0 0.551, 25W 0.253 nmol/L, -54.1%, (p < 0.0001)], SHBG [DMPA-IM D0 45.0, 25W 32.7 nmol/L, -29.8% (p < 0.0001); NET-EN D0 50.2, 25W 17.6 nmol/L, -65.1% (p < 0.0001)], and calculated free testosterone levels [DMPA-IM D0 6.87, 25W 5.38 pmol/L, -17.2% (p = 0.0371); NET-EN D0 6.00, 25W 3.70, -40.0% (p < 0.0001)]. …"

Loss of <i>FGR41</i> modestly delays hyphal development <i>in vitro</i>. حسب Andrew S. Wagner (11331477)

Apicoplast inhibitors decrease global parasite prenylation in the second IDC after treatment. حسب Kit Kennedy (4915510)

Affinity analysis results (with a confidence level above 50%). حسب Marta R. Jabłońska (8491404)

Fig 5 - حسب Debarpan Dhar (724473)

Human cerebral organoids treated with VPA show a decreased size, impaired neurogenesis, and induction of senescence in NE cells. حسب Muriel Rhinn (406515)

Deep crypt secretory (DCS) cells are predominantly distributed in the proximal colon, with a progressive decrease towards the distal colon. حسب Daisuke Sugahara (2047696)

MRI imaging and analysis, revealing decreased volume and thickness of placentas exposed to intrauterine inflammation. حسب Solange N. Eloundou (6551627)

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. حسب Kevin Yuswan (19845885)

Exposure to low CO₂ levels decreases ER cholesterol levels. حسب Nityanand Bolshette (17396845)

"…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO₂ levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …"

Principal component analysis (PCA) for the SP domain of native PC and its mutant structures over 200 ns MD simulation times. حسب Mahvash Farajzadeh-Dehkordi (17468232)

Treatment with TDF decreased cell viability and induced morphological changes in hepatic stellate cells. حسب Sung Won Lee (222509)

Overexpression of mC4 decreased membrane capacitance without altering overall excitability. حسب Ashley L. Comer (8299128)

Conditional ablation of <i>Ybx1</i> leads to a reduction in cortical progenitor cell pool and a decrease in cortical thickness. حسب Jian Zhang (1682)

Excel spreadsheet containing, in separate sheets (for each figure), the underlying numerical datas for Figure panels 1A, 1B, 1C, 2B, 3A, 3B, 3C, 4C, 4D, 4E, 4F, 4G, 5B, 8C and 8D. حسب Acharya Balkrishna (5640038)

Thermal denaturation of ZIKV NS2B/NS3^pro and CHIKV nsP2^pro using fluorescence spectroscopy. حسب Raphael J. Eberle (9286932)

A decrease in the synthesis of all viral proteins in A549 cells infected with PIV5-W3 is observed by 36h p.i. حسب Dan F. Young (6321425)

Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant حسب Ittipat Meewan (7455041)

"…Hepatitis C virus (HCV) is a human pathogen with high morbidity. The HCV NS3/4A protease is essential for viral replication and is one of the top three drug targets. …"

Fig 5 - حسب Meng-Jia Lau (7827683)

Fig 5 - حسب Melissa A. Hill (13170105)