Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO حسب Qing-Yuan Wang (11571890)

"…Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…"

Antimicrobial activity of RP-1 peptide conjugate with ferrocene group حسب Natalia C. S. Costa (8626206)

"…The Fc-RP1 presented anti-amastigote activity against <i>Leishmania amazonensis</i> (IC₅₀ = 0.25 μmol L^–1). In comparison with amphotericin B, a second-line drug approved for leishmaniasis treatment, (IC₅₀ = 0.63 μmol L^-1), Fc-RP1 was more active and showed a 2.5-fold higher selectivity index. …"

Medium-Ring Keto Bislactams with Antischistosomal Activity حسب Rongguo Ren (2943366)

"…Aryl substitution with EWG functional groups decreased the chemical stability. These compounds were relatively polar with the measured LogD_7.4 values ranging from <0 to 2.4, had kinetic aqueous solubilities between 40 and >320 μM, and had relatively low cytotoxicities with IC_50s ranging from 52 to >390 μM. …"

Effects of betaine on diuresis [μl/min/g k.w.], HR [bpm] and MABP [mmHg] in anesthetized Spontaneously Hypertensive rats and Wistar Kyoto normotensive rats. حسب Izabella Mogilnicka (13965422)

Zwitterion-Functionalized Cuprous Oxide Nanoparticles for Highly Specific and Enzymeless Electrochemical Creatinine Biosensing in Human Serum حسب R. K. Rakesh Kumar (14241205)

الموضوعات:

1-hr treatment with 10μM PF573228 or 10μM PD98059 in Caco-2 cells. حسب Sema Oncel (10152053)

Phenotypic and genotypic analysis following treatment of incrossed heterozygous <i>bmp4</i>^{<i>st72/+</i>} zebrafish with 0 μM, 0.25 μM and 0.5 μM PTC124. حسب Max Krall (6631025)

"…The probability of tail fin defect decreased from 81.08% to 74.07% and 37.50% as the dose increased to 0.25 μM and 0.5 μM. …"

Germ cell size decreases before corpse formation. حسب Tea Kohlbrenner (19476160)

The raw data of ¹³⁷Cs activity concentrations in <i>Aralia elata</i> buds and environmental variables analyzed in Sakai et al. Exploring simple ways to avoid collecting... حسب Masaru Sakai (1669627)

الموضوعات:

¹³⁷Cs activity concentrations in <i>Aralia elata</i> buds collected in Iitate village, Fukushima from 2014 to 2022. حسب Masaru Sakai (1669627)

الموضوعات:

Relationship between the ¹³⁷Cs inventory in the soil and the dose rate on the soil surface. حسب Masaru Sakai (1669627)

الموضوعات:

Results of the linear mixed model used to test for effects of the dose rate at the soil surface, organic soil layer thickness, and slope steepness on the ¹³⁷Cs activity... حسب Masaru Sakai (1669627)

الموضوعات:

Fig 2 - حسب Masaru Sakai (1669627)

الموضوعات:

Fig 3 - حسب Masaru Sakai (1669627)

الموضوعات:

The decrease or inhibition of Hsp90 induced REST degradation. حسب Raúl Orozco-Díaz (7067624)

"…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …"

HFD induces LDs and decreases ER and mitochondria in nephrocytes. حسب Aleksandra Lubojemska (10746241)

"…Scale bar = 50 μm. (<b>D</b>) In pericardial nephrocytes (dashed outlines), LDAH::GFP localises primarily to the ER (marked with anti-KDEL antibody) in STD larvae but to the surface of ER-associated LDs (marked with the neutral lipid dye LipidTOX) in HFD larvae. …"

Kinase profiler assay of 1C8 (10 μM). حسب Florentin Pastor (19852287)

In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin حسب Stephanie A. Eytcheson (4284421)

الموضوعات:

Top 10 pathways with the lowest p-value. حسب Rizka Fatriani (17485787)

"…<i>paniculata</i> ethanolic extract starting at concentrations 62.5 μg/ml and 15.625 μg/ml, respectively. These results indicate that <i>M</i>. …"

Inhibition of Jag2 effectively ameliorates hypoxia-induced PH in rats. حسب Hanhan Liu (568151)

الموضوعات: