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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…This study aims to investigate the inhibitory effect of metformin on VISTA via AHR in melanoma cells (CHL-1, B16) and animal models. VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of -0.16 mmol/L and -0.48 mmol/L, respectively. …”
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Extraction and characterization of biofunctional lignocellulosic fibers from Pulicaria undulata plant and the effect of alkali treatment on their bio-physicochemical properties
Published 2024“…The average yield of raw fibers obtained was 28.1 %. The raw fibers of P. undulata were rich in cellulose (36.2 %), followed by hemicellulose (30.3 %), lignin (16.2 %), moisture (11.1 %), and pectin (3.9 %). …”
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High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i...
Published 2023“…These key performance indicators were slightly decreased when fingerstick whole-blood samples were used: sensitivity [85.7 %(63.7–97)], specificity [90.0 %,(81.5–96)], good agreement (Cohen's Kappa = 0.7) and very strong correlation (r = 0.9, p < 0.0001) with cobas® e 601. …”
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Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic
Published 2023“…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…”
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Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane
Published 2024“…The results indicated that tensile and flexural strength decreased by 35.16 % and 29.3 % respectively, from S1 to S10. …”
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Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis
Published 2025“…The SSI incidence in LMICs was 8.0 % (95 % CI: 6.0 %–10.0 %) with moderate certainty, while the incidence in HICs was 5.0 % (95 % CI: 4.0 %–7.0 %) with low certainty. …”
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Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis
Published 2023“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”
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Methane production enhancement from Tetraselmis biomass co-digestion using frying oil residue as co-substrate and ultrasonication as pretreatment
Published 2023“…Interestingly, compared to untreated Tetraselmis biomass, sonication pretreatment using specific energy of 1.6 kJ/g VS significantly improved specific methane production by 60.5%. …”
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
Published 2022“…Its values in the Gulf ranged from −50 to −310 μmol kg−1 implying CaCO3 precipitation. …”
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Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties
Published 2022“…The addition of up to 6.75 wt% of adamantane in diesel significantly increased the smoke point of diesel from 18 to 29 mm (and threshold sooting index decreased by 44%), indicating a drastic drop in fuel sooting tendency. …”
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Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
Published 2024“…The global incidence rate of otitis media was 4958·9 per 100 000 (3705·4 to 6658·6) in 2021, a decrease of 16·3% (–18·1 to –14·0) from 1990, when the incidence rate was 5925·5 per 100 000 (4371·8 to 8097·9). …”
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