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Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells
Published 2003“…Overexpression of hAT1R and hAT1R GFP decreased both basal cytosolic and nuclear Ca2+. In normal hVSMCs and low hAT1R GFP overexpressing hVSMCs, Ang II (10 15 to 10 4 M) induced a dose-dependent sustained increase of [Ca]c and [Ca]n with an EC50 near 5 × 10 11 and 5 × 10 9 M, respectively. …”
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Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability
Published 2021“…OPC paste and mortar with TWW were first prepared and compared with the permissible limits specified in ASTM C1602/C1602M − 18 provisions. After that, ten concrete mixes were prepared with different ratios of TWW (0%, 25%, 50%, and 100%), FA (0%, 20%, and 35%), and CN (0% and 3%) and tested for fresh slump and density, compressive and flexural strengths, electrical resistivity, porosity, and chloride permeability. …”
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One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes
Published 2022“…The participants used the sensor 88.4 ± 6.5% of the time with Auto Mode usage 85.6 ± 7.4% during 12 months of HCL system use. HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline, to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at 3 months (p = 0.02) and remained stable to 7.1 ± 0.6 (54 ± 6.6 mmol/mol) at 12 months (p = 0.02). …”
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Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media
Published 2021“…As the nanocomposite concentration was increased from 50 to 500 µg/mL, the specific sulfate reduction rate (SSRR) decreased from 0.278 to 0.036 g-sulfate/g-VSS*day showing a relative sulfate reduction inhibition of 86.64% as compared to that of control. …”
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Treatment with a Combination of Metformin and 2-Deoxyglucose Upregulates Thrombospondin-1 in Microvascular Endothelial Cells: Implications in Anti-Angiogenic Cancer Therapy
Published 2019“…Assays for cell proliferation, migration and tubulogenesis were also performed. We observed robust up-regulation of anti-angiogenic thrombospondin-1 (TSP1) and increased TSP1-CD36 co-localization with a marked decrease in the levels of phosphorylated vascular endothelial growth factor receptor-2 (pVEGFR2; Y1175) in 2DG (5 mM) exposed cells treated with metformin (2 mM). …”
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Total hip arthroplasty: Evolution of the use of dual mobility cups in Lebanon
Published 2018“…Having no national registry, we conducted a series of investigations with each registered company providing THA implants on the Lebanese territory. …”
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Solar hydrogen production via thermochemical magnesium oxide – Magnesium sulfate water splitting cycle
Published 2020“…Overall analysis confirms that although the rise in the molar flow rate of Ar from 1 to 50 mol/s results in a decrease in the thermal reduction temperature from 1490 K to 1282 K, the solar-to-fuel energy conversion efficiency is adversely affected and reduces from 47.7% to 18.1%. …”
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Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17
Published 2020“…For piped water, the safest water facility type, access increased from 40·0% (95% uncertainty interval [UI] 39·4–40·7) to 50·3% (50·0–50·5), but was lowest in sub-Saharan Africa, where access to piped water was mostly concentrated in urban centres. …”
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The economics of oil, biofuel and food commodities
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Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…ResultsThe course included 18 participants (10 female, 8 males; average age 40.18 ± 8.46 years) categorized as novice (n = 10, <3 years’ experience), intermediate (n = 5, 3-5 years), and expert (n = 3, >5 years). Video evaluations did not reveal significant differences due to short-term training. …”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…In addition, treated tumors showed significant dose-dependent decrease in mitotic activity index by 36.5% and 51% in comparison with the control group. …”
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Performance Analysis of FSO Communications With Diversity Methods
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Simultaneous Bilateral Neck of Femur Fracture in a Young Adult with Underlying Metabolic Disturbances
Published 2020“…<em>Conclusion</em>. We report this rare case of bilateral neck of femur fracture in a young adult after a generalized seizure attack with underlying metabolic disturbances. …”
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Effect of Construction Void Defects on Flexural and Axial Load Capacity of Reinforced Concrete Members
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Did the periodic intensification of routine immunisation strategy (Intensified mission Indradhanush) reduce the demand for pediatric antibiotic formulations in India?
Published 2025“…We conducted interrupted time series analyses by fitting a Poisson regression model. …”
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Optimization of Vapor Compression Refrigeration Cycles with Clathrate Hydrates Thermal Energy Storage
Published 2021Get full text
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