Understanding the progress and challenges in the fields of thermo-catalysis and electro-catalysis for the CO₂ conversion to fuels حسب V. S. K. Yadav (17727660)

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... حسب Michael, Brauer

"…From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer حسب Claudio Vernieri (9744243)

"…<p dir="ltr">In tumor-bearing mice, cyclic fasting or fasting-mimicking diets (FMD) enhance the activity of antineoplastic treatments by modulating systemic metabolism and boosting antitumor immunity. Here we conducted a clinical trial to investigate the safety and biological effects of cyclic, five-day FMD in combination with standard antitumor therapies. …"

Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism حسب Tarek Fouda (18472476)

"…</p><h3>Results</h3><p dir="ltr">Patients within the PTH target range of 150 to 500pg/ml improved from 8% in June 2021 (on Cinacalcet) to 54% in June 2023 (on Etelcalcetide) (p=0 .0032) while patients with PTH above 1,000pg/ml decreased from 50% to 4% during the same period (p=0.00001) (Figure 2). …"

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S., El-Shoukrofy

"…Compound 2a activated PPARγ with an EC50 value of 3.4 μM in a Gal4-hybrid reporter gene assay, indicating partial agonistic action. …"
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Technical assessment of different extraction methods and transcriptome profiling of RNA isolated from small volumes of blood حسب Mahesh Kumar Reddy Kalikiri (17886695)

"…We have used the QuantSeq 3′ FWD mRNA-Seq Library Prep kit to prepare RNA-seq libraries, which were sequenced on the Illumina NextSeq 500 system. …"

Postmicturition dribble in men with no previous urogenital surgery: Systematic review and meta‐analysis of treatment modalities حسب Ahmed Albakr (14058051)

"…Meta‐analyses of the two PDE5 inhibitors studies showed a large effect size with high heterogeneity for decreased PMD volume favoring PDE5 inhibitors over placebo (g = −0.86, 95% confidence interval [CI] −1.75; 0.02, p = 0.05; I2 = 88%); and a significant improvement equivalent to −1.06 points on the Hallym PMD Questionnaire score with no discernable heterogeneity (95% CI −1.65; −0.47, p = 0.0004; I2 = 0%), favoring PDE5 inhibitors compared to controls.…"

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway حسب Olfa Khalifa (10914452)

"…We established steatotic HepG2 cells by incubating the cells with 400 µM oleic acid (OA) overnight. …"

miRNA-dependent regulation of STIM1 expression in breast cancer حسب Rashmi P. Kulkarni (18618634)

"…The ER Ca²⁺ sensor STIM1 and Orai plasma membrane Ca²⁺ channels molecularly mediate SOCE. Here we investigate the role of the microRNA machinery in regulating STIM1 expression. …"

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S. El-Shoukrofy (19646815)

"…Compound 2a activated PPARγ with an EC₅₀ value of 3.4 μM in a Gal4-hybrid reporter gene assay, indicating partial agonistic action. …"

The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere حسب Sara H. Al-Hadidi (17821196)

"…<p dir="ltr">The date palm (<i>Phoenix dactylifera</i>) is an important cultivated crop in arid areas. Here, we studied the effect of plant genotype and type of fertilizers on the eukaryotic community structures of the date palm rhizosphere. …"

Spatial, temporal, and demographic patterns in prevalence of chewing tobacco use in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Diseas... حسب Parkes J Kendrick (9714851)

"…We also compared these trends to those of smoked tobacco over the same time period. …"

Effect of sintering temperature of NBT–6BT lead-free ceramics on the structural, ferroelectric and piezoelectric properties حسب Slimani, Ahmed

"…It is found that the optimal ferroelectric and piezoelectric values were obtained at 1150 °C (P r = 27 µC/cm 2 , E c = 3.89 kV/mm and d 33 = 110 pC/N). According to these results, we suggest that 850 °C and 1150 °C can be considered as optimal calcination and sintering temperature in NBT-6BT ceramic, respectively.…"
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Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study حسب Spencer L James (8673927)

Role of Edge Groups in Defining the Stability of Aromatic Molecules Under Electron Irradiation حسب Y. Tong (18394389)

"…<p dir="ltr">Electron irradiation is known to be an important physical tool in tuning the properties of self-assembled organic molecules. Here, we use X-ray photoelectron spectroscopy (XPS) measurements to study the effect of electron bombardment on the structural properties of dithiol aromatic molecules, where the sulfur atoms are either in direct conjugation with phenyl rings (case of Biphenyl-4,4′-dithiol, BPN) or separated by a methylene group (case of 5,5′-bis(mercaptomethyl)-2,2′-bipyridine, BPD). …"

The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017 حسب Arash Etemadi (330880)

"…Globally, 38·2% (21·1–57·8) of the age-standardised DALYs were attributable to high-sodium diet in both sexes combined, and 24·5% (20·0–28·9) of the age-standardised DALYs were attributable to smoking in males. …"

Past and future climate effects on population structure and diversity of North Pacific surfgrasses حسب Ana I. Tavares (6942986)

"…We predicted the distribution of the species for the present, LGM, and near future (RCP 8.5, no climate mitigation) using Species Distribution Models (SDMs).…"

The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study حسب Aksam Yassin (14779204)

"…Blood samples were taken at every other visit to measure levels of total T (TT), calculated free T, sex hormone-binding globulin (SHBG), estradiol, luteinizing hormone (LH), follicle-stimulating hormone (FSH), progesterone and prolactin. We observed an increase in TT of 15.5 nmol/L (<i>p</i> < 0.0001), a reduction in SHBG of 10.5 nmol/L (<i>p</i> < 0.0001) and an increase in calculated free T of 383.04 pmol/L (<i>p</i> < 0.0001) over the study period. …"

Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis حسب Fateen Ata (12217764)

"…The use of TT was significantly associated with increased survival (27.1 % vs. 12.5 %, p < 0.001). In a multivariate logistic regression model, massive PE features significantly increased the odds of death (OR: 29.3, CI: 4.86–181.81, p < 0.001), whereas, treatment with anticoagulation (AC) alone (OR: 0.1, CI: 0.027–0.356, p < 0.001), TT (OR: 0.065, CI: 0.019–0.26, p < 0.001), surgical thrombectomy (ST) (OR: 0.047, CI: (0.010–0.23), p < 0.001), or percutaneous thrombectomy (PT) (OR: 0.12, CI: 0.020–0.84, p = 0.032) significantly decreased odds of death.…"

XPS and material properties of raw and oxidized carbide-derived carbon and their application in antifreeze thermal fluids/nanofluids حسب Ismail W. Almanassra (14151321)