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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound <b>2a</b>. …”
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Subarachnoid hemorrhage associated with tadalafil
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Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS
Published 2018“…The glucose disposal rate during the lipid infusion was reduced following exercise in PCOS, indicating decreased IR (67 ± 5 vs. 50 ± 7%, p = 0.02), but IR was not altered in controls (49 ± 7 vs. 45 ± 6%, p = 0.58). …”
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Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
Published 2021“…The second-best method was the Horizontal Louvers, where it achieved a reduction in energy consumption by 7.7% compared to the base case, and in daylight, it achieved a decrease of 50% in Both selected months. …”
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf)
Published 2022“…Its values in the Gulf ranged from −50 to −310 μmol kg−1 implying CaCO3 precipitation. …”
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Temperature Effect on the Mechanical Properties of Carbon, Glass and Carbon-Glass FRP Laminates
Published 2015“…Based on the test results, the decrease in the mechanical properties of the composite C and G sheets was more severe than those of the composite hybrid CG sheets. …”
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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…</p> <p>Results: The BCAA-restricted diet significantly reduced circulating BCAA concentrations by ~50% i.e., baseline 437 ± 60 to 217 ± 40 µmol/L (p < 0.005). …”
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Strengthening of thin reinforced concrete slabs with CFRP laminates
Published 2016“…Two groups of slab specimens having a thickness of 75 mm were cast with a concrete compressive strength of 50 MPa and 100 MPa, respectively. …”
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SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Published 2019“…The <i>K</i><sub><em>i</em></sub> values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. …”
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Lateral extension induces columnar mesomorphism in crucifix shaped quinoxalinophenanthrophenazines
Published 2015“…Reported here is the columnar mesomorphism of board shaped dyes based on quinoxalino[2′,3′:9,10]phenanthro[4,5-abc]phenazine (TQPP) derivatives that was induced by an increase in lateral bulk. …”
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Potent anti-tumor promoting effects of Daucus carota oil extract in mice
Published 2008“…Tumor volume was decreased by 99, 91 and 70% following topical treatments with 100, 50 and 5% oil extract respectively. …”
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Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO<sub>2</sub>- saturated saline solution
Published 2023“…Lastly, potentiostatic testing of steel with AGGPAM at an applied potential of 50 mV illustrated surface protection and decreased current over a prolonged time. …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…We also found increased levels of LAMP-1 and LAMP-2A both <i>in vitro</i> and <i>in vivo</i>, along with decreased levels of α-synuclein. …”
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