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Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
Published 2024“…FindingsIn 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). …”
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82
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
Published 2020“…Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. …”
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Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
Published 2020“…<p dir="ltr">Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. …”
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Antioxidant and hepatoprotective activities of the oil fractions from wild carrot (Daucus carota ssp. carota)
Published 2015“…The sesquiterpene-rich fraction F1 had the highest FIC ability (IC50 = 0.28 mg/ml). Pretreatment with F1 and F4 reversed the CCl4-induced decrease in SOD, CAT, and GST levels and reduced significantly hepatic damage. …”
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85
The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models
Published 2021“…Additional recent studies showed that Cannabis sativa oil extract (COE) demonstrated potent anti-inflammatory effects. DCOE (100 mg/kg body weight) and HC (25 and 50 mg/kg body weight) were administered daily to rats for 10 days, and a single dose of cisplatin (7.5 mg/kg body weight) was administered on day five. …”
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masterThesis -
86
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer
Published 2017“…Treatment of HaCaT-ras A5 and HaCaT-ras II4 cells with F2 fraction resulted in the accumulation of cells in the sub-G1 apoptotic phase and decreased the population of cells in the S and G2/M phases. …”
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87
Proteome analysis of Candida albicans cell wall mutants. (c2011)
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masterThesis -
88
The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis
Published 2018“…Treatment with HC25, HC5%Top or Cisplatin showed a significant decrease in papilloma yield and volume. …”
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The antioxidant and anticancer effects of Wild Carrot oil extract
Published 2012“…The FRAP value was 164 ± 5.5 µmol FeSO4/g, and the IC50 values for DPPH and FIC assays were 2.1 ± 0.03 mg/ml and 0.43 ± 0.02 mg/ml, respectively. …”
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…Results β-2-himachalen-6-ol showed a dose-dependent decrease in cell survival with an IC50 and IC90 of 8 and 30 μg/ml, respectively. …”
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91
Cell surface proteome characterization of the Candida albicans DSE1 mutant. (c2011)
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92
Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
Published 2017“…Results: The results showed a decrease in the proliferation of U937 after 48hrs with IC50 at 24mg/ml. …”
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Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon
Published 2011“…Increasing the dose to 500 mg/kg body weight caused a significant decrease in stool water content. …”
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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults
Published 2022“…The mean baseline 25(OH)D3 concentration was 16.92±7.23ng/ml in the vitamin D group and 16.44±5.91 ng/ml in the control group (p =0.76). …”
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95
Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
Published 2023“…Group IV (PAR) received 600 mg/kg of PAR orally; V (PAR + IL-35) and VI (PAR + TYHO); rats received 600 mg/kg of PAR orally and i.p injection of IL-35 (200 ng/kg) or THYO (0.5 mg/kg), respectively. …”
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β-2-himachalen-6-ol
Published 2016“…In this study, we report the isolation and identification of the major compound responsible for the anti-cancer activity of DCOE along with the mechanism of action involved. GC–MS and NMR spectroscopy revealed the identity of the major compound as β-2-himachalen-6-ol, a novel sesquiterpene unique to the Lebanese wild carrot. β-2-Himachalen-6-ol demonstrated potent anti-cancer activity against B16F-10, Caco-2, MB-MDA-231, A549 and SF-268 cancer cells (IC50 13–4 µg/ml; 58–18 µM), with SF-268 cells being the most sensitive. …”
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Efficacy of Cannabidiol Combination with Cisplatin or Paclitaxel against Platinum-Resistant Ovarian Cancer Cell Lines
Published 2022“…Monotherapy with CBD demonstrated a dose-dependent tumor growth inhibition at 72h, with the IC50 being 12.5 μg/ml for OVCAR-3 cell line and 12.3 μg/ml for SK-OV-3 cell line. …”
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100
Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities
Published 2009“…Results showed that 50mg/kg and 100mg/kg caused 20.87 and 80.10%, respectively, compared to 41.70% for cimetidine at 11.5mg/kg BW dose. …”
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