Transferrin Receptor-Mediated Cellular Uptake of Fluorinated Chlorido[<i>N</i>,<i>N</i>′‑bis(salicylidene)-1,2-phenylenediamine]iron(III) Complexes by Astrid Dagmar Bernkop-Schnürch (17461895)

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Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases by Xiao Li (107004)

“…In this study, we first identified several hit compounds against CARM1 by structure-based virtual screening (IC₅₀ = 35.51 ± 6.68 to 68.70 ± 8.12 μM) and then carried out chemical structural optimizations, leading to six compounds with significantly improved activities targeting CARM1 (IC₅₀ = 18 ± 2 to 107 ± 6 nM). …”

BT9 exhibits a dose- and time-dependent cytotoxic effect on medulloblastoma. by Zahra Motahari (6814013)

Variable included in analysis. by Molebatsi Moholola (20513371)

“…</p><p>Results</p><p>Our final study sample consisted of 3 256 clients, half of which received case management (N = 1 628), 1084 (33%) with a first VL in study of 50–399 copies/ml, 404 (12%) 400–999 copies/ml and 1768 (54%) >1000 copies/ml. …”

Full dataset of the study. by Molebatsi Moholola (20513371)

“…</p><p>Results</p><p>Our final study sample consisted of 3 256 clients, half of which received case management (N = 1 628), 1084 (33%) with a first VL in study of 50–399 copies/ml, 404 (12%) 400–999 copies/ml and 1768 (54%) >1000 copies/ml. …”

The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin... by Chanel Avenant (409756)

“…Both contraceptives substantially decreased, from D0 to 25W, the total testosterone [DMPA-IM D0 0.560, 25W 0.423 nmol/L, -24.3% (p < 0.0001); NET-EN D0 0.551, 25W 0.253 nmol/L, -54.1%, (p < 0.0001)], SHBG [DMPA-IM D0 45.0, 25W 32.7 nmol/L, -29.8% (p < 0.0001); NET-EN D0 50.2, 25W 17.6 nmol/L, -65.1% (p < 0.0001)], and calculated free testosterone levels [DMPA-IM D0 6.87, 25W 5.38 pmol/L, -17.2% (p = 0.0371); NET-EN D0 6.00, 25W 3.70, -40.0% (p < 0.0001)]. …”

The S75A mutation of LeishIF4E3 leads to a decrease in granule formation in response to PBS starvation and to a reduced interaction with LeishIF4G-4. by Rohit Shrivastava (6459608)

RDV and EIDD2801 EC₅₀ and fold-change in VeroE6-ACE2-TMPRSS2. by Agnieszka M. Szemiel (10196243)

HBV RNaseH inhibitors effects on capsid accumulation occur independent of HBV DNA synthesis. by Daniel P. Bradley (10306893)

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Compound 390 induces HBV capsid accumulation via an ROS-mediated mechanism. by Daniel P. Bradley (10306893)

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1466 does not change total yield of capsids during biochemical assembly reactions. by Daniel P. Bradley (10306893)

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1466 slows the capsid assembly rate in biochemical Cp149 capsid assembly reactions. by Daniel P. Bradley (10306893)

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1466 inhibits capsid accumulation independent of HBV replication. by Daniel P. Bradley (10306893)

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Screening HBV RNaseH inhibitors in HepDES19 cell for effects on capsids and core protein. by Daniel P. Bradley (10306893)

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αHT compound 390 does not affect intracellular capsid accumulation or encapsidated HBV RNA levels in HepG2.2.15 cells. by Daniel P. Bradley (10306893)

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Compound structures and preferential inhibition of the HBV plus-polarity DNA strand. by Daniel P. Bradley (10306893)

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Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Sexual symptoms, (N = 73). by Wafa Y. Ahmed (20727327)

“…<div><p>Deinfibulation [opening the scar of infibulation] is a minor operation involving a vertical incision to the scar to expose the urethra and vagina. …”

Reduced GTPase activity of BipA_N128D. by Eunsil Choi (8271039)

Temperature-sensitive germline immortality exhibit decreased histone methylation. by Katherine Kretovich Billmyre (6524396)