Search alternatives:
teer decrease » greater decrease (Expand Search)
mean decrease » a decrease (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
12 wt » 2 wt (Expand Search), 1 wt (Expand Search)
50 c » 5 c (Expand Search), 50 μ (Expand Search), 50 _ (Expand Search)
teer decrease » greater decrease (Expand Search)
mean decrease » a decrease (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
12 wt » 2 wt (Expand Search), 1 wt (Expand Search)
50 c » 5 c (Expand Search), 50 μ (Expand Search), 50 _ (Expand Search)
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…GCase activity measured by 4-MU in liver (B) measured as follows: WT 4mo 93.69±7.16, HOM 4mo 3.90±0.21, WT 8mo 112.40±6.84, HOM 8mo 1.50±0.19, WT 12 mo 96.79±7.44, HOM 12mo 3.50±0.58. …”
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The apparent Ca<sup>2+</sup> affinity of release is decreased by hydrophobic mutations.
Published 2020“…The significant rightward shift in the curve (EC50, non overlapping confidence intervals) indicates a decrease in the apparent Ca<sup>2+</sup> affinity of neurotransmitter release.…”
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