Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

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Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

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Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. by O’Llenecia S. Walker (8486163)

Decreasing fluconazole susceptibility of clinical South African <i>Cryptococcus neoformans</i> isolates over a decade by Serisha D. Naicker (8648370)

Shows the 5′ region and the exons of the <i>C3</i> gene in the vertical line and the three new SNPs that we found by sequencing. by Yonghui Wang (287491)

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Partial correlation of <i>ε</i>_max (left column) and IC₅₀ (right column) estimates at 10 days and 20 days (first and second bar of each color, respectively) o... by Hope Murphy (8843516)

Distribution Coefficients of the REEs, Sr, Y, Ba, Th, and U between α‑HIBA and AG50W-X8 Resin by Haoyu Li (1672648)

“…However, only limited REE partition data between α-HIBA and cation resins exist, which makes it challenging to develop and optimize purification techniques using this platform. Here, we report distribution coefficients (<i>K</i>_d) of REEs, as well as Sr, Y, Ba, Th, and U, between α-HIBA at pH = 4.50 and AG50W-X8 cation-exchange resin, obtained by batch equilibration experiments. …”

Inhibition of PKCδ causes a decrease in viral replication. by Brian D. Carey (6092747)

miR-200c decreases KLOTHO expression in HK-2 cells by translational repression. by Kenichi Morii (6843554)

Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

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Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

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siRNA Knockdown of PKCδ decreases phosphorylation of VEEV capsid. by Brian D. Carey (6092747)

Atomically Precise Au₄₂ Nanorods with Longitudinal Excitons for an Intense Photothermal Effect by Yingwei Li (701628)

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Discovery of Triazolyl Derivatives of Cucurbitacin B Targeting IGF2BP1 against Non-Small Cell Lung Cancer by Fan-Fan Shang (16953264)

“…Among them, derivative <b>A11</b> had the most potent antiproliferative activity against A549 lung cancer cells (IC₅₀ = 0.009 μM) and was approximately 10-fold more potent than CuB, while the cytotoxicity of <b>A11</b> toward normal L02 cells was about 10-fold less potent, indicating a much wider therapeutic window than CuB. …”

The PRAME-AS knockout cells showed a decrease in migration, proliferation, stemness, and viability. by Zahra Hosseininia (22265113)

ROS and superoxide decrease in the dormant form of mycobacteria. by Amar Yeware (7115063)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. by Dennis Ochola (11626912)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 17 covariates selected after recursive feature selection. by Dennis Ochola (11626912)

Preclinical Evaluation of ¹³¹I/¹⁸F‑Labeled Covalent Small-Molecule Inhibitors for STING Status Imaging by Jianyang Fang (11301298)

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Preclinical Evaluation of ¹³¹I/¹⁸F‑Labeled Covalent Small-Molecule Inhibitors for STING Status Imaging by Jianyang Fang (11301298)

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