Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”
Get full text
Get full text
Get full text

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... by Salma, Younes

“…We measured the levels of neutralizing total antibodies (NtAbs), anti-S-RBD IgG, and anti-S1 IgA titers among VN and NI up to ∼10 months from administration of the first dose, and up to ∼7 months from SARS-CoV-2 infection, respectively. …”
Get full text
Get full text
Get full text

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
Get full text
Get full text
Get full text

Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic by Turki, O.

“…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. The incorporation of Dy was found to enhance the EC responsivity coefficient ζ = iT/ΔE), with a best value of ζ = 0.24 K.mm/kV for y = 0.02.…”
Get full text

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
Get full text
Get full text
Get full text

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
Get full text
Get full text
Get full text

Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Fiona B, Bennitt

“…The rate of HAP-attributable DALYs was higher for males (1530·5, 1023·4–2263·6) than for females (1318·5, 866·1–1977·2). …”
Get full text
Get full text
Get full text

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …”
Get full text
Get full text
Get full text

Production of flexible nanocomposite membranes for x-ray detectors by Ahmad I., Ayesh

Get full text
Get full text
Get full text

Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review by Sunji, Nadine

“…Post-COVID-19 onset, 1.7 % of patients tested positive for any STI compared with 1.1 % pre-COVID-19 onset (OR: 1.5, 95%CI: 0.8–2.7). Close to 90 % of all positive diagnoses were among MSM. …”
Get full text
Get full text
Get full text

Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis by Nazmul, Islam

“…Meta-regression showed a significant decrease in SSI incidence in HICs. Maternal factors, procedural aspects, and care quality were associated with SSI. …”
Get full text
Get full text
Get full text

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil, Shallik

“…Our statistical analysis has shown that significantly lower ROX index (5.07 ± 1.66, p = 0.028) and PaO2/FiO2 (100 ± 27.51, p = 0.031) are associated with HFNO failure, while a significantly lower respiratory rate (RR) (23.17 ± 4.167, p = 0.006) is associated with HFNO success. …”
Get full text
Get full text
Get full text

Human health risks associated with the consumption of groundwater in the Gaza Strip by Basem, Shomar

“…On the other hand, nitrate (NO3) decreased by 30 %, due to expansion of the sewer network and decrease in the number and distribution of septic tanks. …”
Get full text
Get full text
Get full text

Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) by Connor, Izumi

“…Its values in the Gulf ranged from −50 to −310 μmol kg−1 implying CaCO3 precipitation. …”
Get full text
Get full text
Get full text

Empirical evaluation of change in crash risk due to lane marking reallocation: A case study in Kochi City, Japan by Hiroaki, Nishiuchi

“…In addition, the results indicate that the PICUD value tends to decrease (i.e., the crash risk tends to increase) with increasing speed of the following vehicle relative to the leading vehicle. …”
Get full text
Get full text
Get full text

Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes by Abushanab, Dina

“…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …”
Get full text
Get full text
Get full text

Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... by Hmwe Hmwe, Kyu

“…FindingsIn 2021, diarrhoeal diseases caused an estimated 1·17 million (95% uncertainty interval 0·793–1·62) deaths globally, representing a 60·3% (50·6–69·0) decrease since 1990 (2·93 million [2·31–3·73] deaths). …”
Get full text
Get full text
Get full text

Extraction and characterization of biofunctional lignocellulosic fibers from Pulicaria undulata plant and the effect of alkali treatment on their bio-physicochemical properties by Mohammed, Alsafran

“…The average yield of raw fibers obtained was 28.1 %. The raw fibers of P. undulata were rich in cellulose (36.2 %), followed by hemicellulose (30.3 %), lignin (16.2 %), moisture (11.1 %), and pectin (3.9 %). …”
Get full text
Get full text
Get full text

Design and analysis of PV fed high-voltage gain DC-DC converter using PI and NN controllers by Madisa V.G., Varaprasad

“…The performance and analysis of the modified converter were described in detail with the help of both controllers. Here, 48 V is doubled to 400 V. By modifying the converter's parameters, its behavior is evaluated. …”
Get full text
Get full text
Get full text

Mixed siliciclastic-carbonate-evaporite sedimentation in an arid eolian landscape: The Khor Al Adaid tide-dominated coastal embayment, Qatar by John M., Rivers

Get full text
Get full text
Get full text