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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound <b>2a</b>. …”
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Extraction and characterization of biofunctional lignocellulosic fibers from Pulicaria undulata plant and the effect of alkali treatment on their bio-physicochemical properties
Published 2024“…The average yield of raw fibers obtained was 28.1 %. The raw fibers of P. undulata were rich in cellulose (36.2 %), followed by hemicellulose (30.3 %), lignin (16.2 %), moisture (11.1 %), and pectin (3.9 %). …”
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183
Managing Endothelial Dysfunction in COVID-19
Published 2022“…Pharmacologically targeting the different mechanisms of endothelial dysfunction may improve clinical outcomes and lead to reduced morbidity and mortality Methods In this pilot, double-blind, placebo-controlled, randomized clinical trial we assigned patients who were admitted to the hospital with mild, moderate, or severe COVID-19 infection to receive, on top of optimal medical therapy, either an endothelial protocol consisting of (Nicorandil, L-arginine, Folate, Nebivolol, and Atorvastatin) or placebo for up to 14 days. …”
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Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System
Published 2013“…The effluent of the control treatment showed 50%, 63%, 46%, and 90% reduction for the same parameters as compared to the influent. …”
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185
Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats
Published 2023“…Thus, CBD has the potential to decrease HbA1C in diabetic patients (Diabetes Mellitus type 1) and improve their lives. …”
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186
Interactions between riluzole and ABCG2/BCRP transporter
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187
Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning
Published 2025“…This approach is also applicable to the application of inexact preconditioners, such as sparse approximate inverse preconditioners used in Krylov subspace methods. In this work, we develop an adaptive precision sparse approximate inverse preconditioner and demonstrate its use within a five-precision GMRES-based iterative refinement method. …”
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Part II.: Dissimilar friction stir welding of nickel titanium shape memory alloy to stainless steel – microstructure, mechanical and corrosion behavior
Published 2021“…Corrosion properties of the weld zone investigated in 3.5 wt. % NaCl solution showed moderately inferior corrosion resistance of dissimilar weld, compared to individual base metals, as characterized by the surface film impedance and corrosion current density. …”
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190
Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study
Published 2024“…Hepatic glucose output increased from 0.6 (0.5–0.7) to 1.5 (1.3–1.7) mmol/min, while arterial lactate increased from 0.8 (0.7–0.9) to 9.0 (8.1–9.9) mmol/L (<i>P</i> < 0.05) despite a rise in hepatic lactate uptake. …”
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Optimum sizing of steam turbines for concentrated solar power plants
Published 2012“…For capacity sizes of 10kWe up to 50MWe, the steam turbine efficiency increases and the steam turbine expected specific capital cost of the power block decreases at a high rate, whereas for larger sizes they remain almost constant. …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…We also found increased levels of LAMP-1 and LAMP-2A both <i>in vitro</i> and <i>in vivo</i>, along with decreased levels of α-synuclein. …”
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Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients
Published 2015“…Three-year and 5-year overall survival rates were, respectively, 65% and 55% in the combined, 58% and 48% in the classic, and 79% and 39% in the reverse strategy (NS). …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against the human melanoma cell line A375, murine melanoma cell line B16, and B16EGFRvIII, respectively. …”
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Grid electricity demand reduction through applying passive and active strategies for a house in Baghdad, Iraq
Published 2013“…By adopting 1Pearl, it provided 4.33% energy reduction while 2 Pearls can achieve about 4.37% decrease in energy. …”
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SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Published 2019“…The <i>K</i><sub><em>i</em></sub> values of compound 16 were determined to be 0.047 and 0.020 μM for the inhibition of MAO-A and MAO-B, respectively. …”
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Social Media Use and Body Checking Among Lebanese Adults
Published 2022“…Participants (n = 423, 18-50 years old of both genders), filled a questionnaire measuring body checking, social media use, self-esteem, perceived stress and emotional eating. …”
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