Showing 21 - 40 results of 64,295 for search '(((( 50 ms decrease ) OR ( 5 ((nn decrease) OR (a decrease)) ))) OR ( 5 ht decrease ))', query time: 0.93s Refine Results
  1. 21
  2. 22
  3. 23

    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
  4. 24

    Pharmacological Mechanism of the Non-hallucinogenic 5‑HT<sub>2A</sub> Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

    Published 2022
    “…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G<sub>q</sub>, G<sub>11</sub>, and β-arrestin2) coupled to 5-HT<sub>2A</sub> receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”
  5. 25

    5-HT inhibits <i>P</i>. <i>berghei</i> infection in mosquitoes. by Li Gao (131516)

    Published 2024
    “…The purple boxes represent the metabolites of the indole pathway, the blue boxes represent the metabolites of the 5-HT pathway, and the tan boxes represent the metabolites of the kynurenine pathway. …”
  6. 26
  7. 27
  8. 28
  9. 29
  10. 30
  11. 31
  12. 32
  13. 33
  14. 34
  15. 35
  16. 36

    Additional Analysis of visually induced calcium transients in Fig 5. by Maureen M. Sampson (9322886)

    Published 2020
    “…<p>Visually induced calcium transients were recorded in flies expressing L2-split-GAL4>GCaMP6f as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g005" target="_blank">Fig 5</a>. …”
  17. 37

    Additional Analysis of visually induced calcium transients in Fig 6. by Maureen M. Sampson (9322886)

    Published 2020
    “…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …”
  18. 38
  19. 39

    Serotonin modulates L2 neuron visually induced calcium transient kinetics. by Maureen M. Sampson (9322886)

    Published 2020
    “…Light or dark stimuli (A, middle panel, white and black vertical bars respectively) were flashed at random every 5 s for 6 min. …”
  20. 40

    Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor by Anat Levit Kaplan (12126567)

    Published 2022
    “…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”