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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Investigation of solar PV performance under Doha weather using a customized measurement and monitoring system
Published 2016“…Results predict that the maximum power output from a Poly-crystalline panel decreases by around 30% for a dust exposure of five months. …”
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Potential of microalgae as a sustainable feed ingredient for aquaculture
Published 2021“…An increase in fish consumption, combined with a decrease in wild fish harvest, is driving the aquaculture industry at rapid pace. …”
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Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method
Published 2013“…The coercivity of Ni and Ni-Zn mixed ferrites decreased with temperature. The Bloch exponent was 1.5 for all samples. …”
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Combined influence of temperature and flow rate of feeds on the performance of forward osmosis
Published 2016“…The experimental results also showed that the membrane flux increased by 93.3% due to temperature increase from 20 to 26 °C and the flow rate from 1.2 to 3.2 L/min using a 0.5 M NaCl solution as the draw solution and distilled water as the feed solution (FS).…”
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Dynamic workload patterns prediction for proactive auto-scaling of web applications
Published 2018“…The framework is implemented and experimentally evaluated using historical access logs of three real web applications, each with increasing, decreasing, periodic, and randomly varying arrival rate behaviors. …”
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Hyperhydration-induced decrease in urinary luteinizing hormone concentrations of Male athletes in doping control analysis
Published 2019“…However, an adjustment of urinary LH concentrations by specific gravity based on a reference value of 1.020 seems to adequately correct the hyperhydration-induced decrease on the LH levels. - 2019 Human Kinetics, Inc.…”
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Impact of Draw Solution Concentration on Forward Osmosis Process: A Simulation Study
Published 2020“…A solution of low salinity was used as the feed solution in forward osmosis to dilute saline solution (i.e. draw solution) for further desalination. …”
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Potential of halophytes as cattle fodder : A case-study in Pakistan
Published 2016“…For instance, P. antid tale increased the calf weight around 15% when used as green and 8% in case of hay. Feeding Berseem (Trifolium alexandrinum, 15% crude protein) as the only source of concentrate in a diet containing D. bipinnata sustained weight only for about 6-7 weeks after which it started to decrease. …”
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Complex-impedance response of an Ag/TeO2-V2O5/Ag structure
Published 2009“…The ac conductivity of glass samples of composition 50 mol% TeO2 and 50 mol% V2O5 has been analyzed. The samples were prepared by the usual melt-quench method. …”
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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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