Genome-wide association study and meta-analysis of phytosterols identifies a novel locus for serum levels of campesterol حسب Jamil Mahmoud Alenbawi (21546995)

"…<p dir="ltr">Sitosterolemia is a rare inherited disorder caused by mutations in the <i>ABCG</i>_<em>5</em>/<i>ABCG8</i> genes. These genes encode proteins involved in the transport of plant sterols. …"

Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution حسب Kashif Bilal (16896357)

"…In this article, we advance the case of Virtual Network Function (VNF) based service-less architecture for video multicast. …"

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... حسب Samar Shurbaji (9938696)

"…These key performance indicators were slightly decreased when fingerstick whole-blood samples were used: sensitivity [85.7 %(63.7–97)], specificity [90.0 %,(81.5–96)], good agreement (Cohen's Kappa = 0.7) and very strong correlation (r = 0.9, p < 0.0001) with cobas® e 601. …"

Custom foot orthoses improve performance, but do not modify the biomechanical manifestation of fatigue, during repeated treadmill sprints حسب Olivier Girard (409080)

"…</p><h3>Results</h3><p dir="ltr">Distance ran in 5 s decreased from first to last sprint (<i>P</i> < 0.001), yet with higher sprints 1–8 values for both EVA (<i>P</i> = 0.004) and TPU (<i>P</i> = 0.018) versus CON. …"

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 حسب Austin, Carter

"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Brittney S Sheena (9715568)

"…By contrast, all-age and age-standardised death rates due to HBV-related diseases decreased during these periods. We compared estimates for 2019 in 194 WHO locations to WHO-GHSS 2020 targets, and found that four countries achieved a 10% reduction in deaths, 15 countries achieved a 30% reduction in new cases, and 147 countries achieved a 1% prevalence in children younger than 5 years. …"

Electrically conductive hybrid organic crystals as flexible optical waveguides حسب Li, Liang

"…The elements respond rapidly to temperature by curling or uncurling in about 0.2 s, which in one typical case corresponds to exceedingly fast deformation and recovery rates of 2187.5° and 1458.3° , respectively. In cyclic operation mode, their conductivity decreases less than 1% after 10,000 thermal cycles. …"
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The promise of tirzepatide: A narrative review of metabolic benefits حسب Sara Sokary (17337724)

"…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. …"

Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy حسب Abu Saleh Md Moin (6189512)

"…<h2>Introduction</h2> <p>We sought to determine whether chromogranin A-positive hormone-negative (CPHN) endocrine cells are increased in the pancreas of pregnant women, offering potential evidence in support of neogenesis.…"

Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) حسب Anas Hamad (9545771)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: BMC Health Services Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12913-022-08981-5" target="_blank">https://dx.doi.org/10.1186/s12913-022-08981-5</a></p>…"

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity حسب Imran Ramzan (15430807)

"…The BCAA-restricted diet marginally lowered Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) levels: baseline 1.5 ± 0.2 to 1.0 ± 0.1; (p = 0.096).</p> <p>Conclusion: We successfully lowered circulating BCAAs by 50% while maintaining iso-nitrogenous, iso-caloric dietary intakes, and while meeting the recommended daily allowances (RDA) for protein requirements. …"

A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge حسب Salim Al Lahham (16515333)

"…</p><h3>Methods</h3><p dir="ltr">This is a case series that includes 9 patients where we describe a technique that has the potential to enhance the survival of the first dorsal metacarpal artery (FDMA) flap and decreases the rate of distal necrosis via addition of a 5-mm skin bridge to the pedicle and by avoiding tunneling. …"

An ensemble-based machine learning model for predicting type 2 diabetes and its effect on bone health حسب Belqes Alsadi (18695031)

"…Lower sodium levels were found in diabetics, potentially stemming from clinical factors including specific medications, hormonal imbalances, unmanaged diabetes. We believe Dapagliflozin prescriptions in Qatar were associated with decreased Gamma Glutamyltransferase and Aspartate Aminotransferase enzyme levels, confirming prior research. …"

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 حسب Hmwe Hmwe Kyu (8674014)

"…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …"

The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort حسب Ken Van Alsenoy (14150559)

"…Albeit not reaching statistical significance (P = 0.11, η² = 0.12), RE on average improved in EVA (+2.1±4.8% and +2.9±4.9%) and TPU (+0.9±5.9% and +0.9±5.3%) compared to CON at LS and HS, respectively. …"

Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs حسب Salam Salloum-Asfar (656363)

"…Introducing miRNAs, such as miR-294 and miR302/3667, with reprogramming factors, has shown to increase iPSC colony formation. Previously, we identified five transcription factors, GBX2, NANOGP8, SP8, PEG3, and ZIC1, which may boost iPSC generation. …"

Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media حسب Kashif Rasool (2542492)

"…We investigated in detail the inhibition mechanism of SRBs by CS@LS in seawater media. …"

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study حسب Rupert Bourne (603842)

"…Globally, between 1990 and 2020, among adults aged 50 years or older, age-standardised prevalence of blindness decreased by 28·5% (–29·4 to −27·7) and prevalence of mild vision impairment decreased slightly (–0·3%, −0·8 to −0·2), whereas prevalence of moderate and severe vision impairment increased slightly (2·5%, 1·9 to 3·2; insufficient data were available to calculate this statistic for vision impairment from uncorrected presbyopia). …"

Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar حسب Dina Abushanab (10696501)

"…<h3>Background</h3><p dir="ltr">There is a lack of evidence regarding the economic impact of antimicrobial stewardship program (ASP).We sought to evaluate the cost-benefit of the mature ASP use compared to premature ASP use in the adults’ general medicine settings in Qatar. …"

Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study حسب Zlatan Zvizdic (9212371)

"…</p><p><br></p><h3>Results</h3><p dir="ltr">We found eight patients with unilateral acute cryptorchid TT with a prevalence of 8.9% (8/90) among all TT cases. …"