Search alternatives:
wt decrease » we decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
n decrease » nn decrease (Expand Search), a decrease (Expand Search), _ decreased (Expand Search)
c decrease » c decreased (Expand Search), a decrease (Expand Search), rc decreased (Expand Search)
_ decrease » _ decreased (Expand Search)
50 n » 50 ns (Expand Search), 50 ng (Expand Search), 50 _ (Expand Search)
wt decrease » we decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
n decrease » nn decrease (Expand Search), a decrease (Expand Search), _ decreased (Expand Search)
c decrease » c decreased (Expand Search), a decrease (Expand Search), rc decreased (Expand Search)
_ decrease » _ decreased (Expand Search)
50 n » 50 ns (Expand Search), 50 ng (Expand Search), 50 _ (Expand Search)
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GluN2A(D731N) decreases channel open probability.
Published 2017“…(<b>D,E</b>) The channel open probability was evaluated by measuring the degree of MTSEA (200 μM) potentiation using TEVC recordings from <i>Xenopus</i> oocytes expressing the WT GluN2A (<i>left panel</i>) or the mutant GluN2A(D731N) (<i>right panel</i>) coexpressed with GluN1(A652C) at a holding potential of -40 mV in presence of EC<sub>50</sub> concentrations of glutamate with saturating concentration (100 μM) of glycine (open bar) and 0.2 mM MTSEA (closed bar). …”
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The GluN2B-C456Y mutation decreases recombinant NMDAR currents and alters receptor properties.
Published 2020“…<i>n</i> = 4 oocytes for WT (pH IC<sub>50</sub> = 7.49 ± 0.016) and 5 oocytes for C456Y (pH IC<sub>50</sub> = 7.11 ± 0.0075), *<i>P</i> = 0.016, Mann-Whitney. …”
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