MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. حسب Jean Paul Dzoyem (6424445)

الموضوعات:

<i>Nanos1</i>⁺ cells in the bulb decrease after X-ray irradiation or drug treatments. حسب Sosuke Fujita (17691623)

<i>PGRP-LC</i> knockdown in gut mitigates the decrease in lifespan caused by heat-killed <i>A</i>. <i>persici</i>. حسب Taro Onuma (15195377)

Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis. حسب Hiroyuki Mori (512656)

"…<p>(<b>A, B</b>) Adipocytes were treated with 10 μM forskolin or 2 μM CL-316,243 (CL) for 6 hours and secretion of glycerol (<b>A</b>) and NEFA (<b>B</b>) measured (<i>n</i> = 4). …"

Taste bud cell populations are decreased after <i>Sox2</i> deletion in epithelial stem/progenitor cells. حسب Makoto Ohmoto (3065106)

Anti-CXCR3 group decreased number of specific CD8⁺ T cells as well as polyfunctionality after infection with <i>T</i>. <i>cruzi</i>. حسب Camila Pontes Ferreira (6194006)

Inhibition of PKCδ causes a decrease in viral replication. حسب Brian D. Carey (6092747)

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

"…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

"…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …"

Oral administration of TVSE decreases angiogenesis in 4T1 tumors in BALB/c mice. حسب Hyun Sook Lee (8039876)

Behavior of split^<50cM <i>ClvR</i> V2 with linkage. حسب Georg Oberhofer (3401438)

"…<p>Incorporating linkage into split <i>ClvR</i> (split^<50cM <i>ClvR</i> V2) results in a graded increase in drive strength, and duration of <i>Rescue</i>/Cargo/gRNAs at high frequency, as the degree of linkage increases (map distance decreases). …"

Behavior of split^<50cM <i>ClvR</i> V1 with linkage. حسب Georg Oberhofer (3401438)

Orsay virus infection of the <i>lin-8(n2731</i>) synMuv A mutant induces a Muv phenotype indicative of decreased synMuv B gene activity, and 2 different synMuv B mutants produce 50–100× less Orsay virus RNA. حسب Ashwin Seetharaman (615458)

RDV and EIDD2801 EC₅₀ and fold-change in VeroE6-ACE2-TMPRSS2. حسب Agnieszka M. Szemiel (10196243)

The light-induced decrease in frequency in <i>En1</i>-Arch cords is due to a ventral, nonglutamatergic mechanism and is similar in <i>En1</i>-Arch and <i>En1</i>-Arch-tdT spinal co... حسب Melanie Falgairolle (759132)

The T37A substitution increases both H5N6 M1 protein stability and H5N6 viral replication in mammals. حسب Chenxi Wang (284364)

الموضوعات:

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. حسب Laura L. Stafman (6577184)

"…(B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC₅₀ = 6.4 μM, p ≤ 0.05). (C) HuH6 cells were plated and allowed to reach 80% confluence, at which time the media was changed for fresh media (0, 5, or 8 μM FTY720) and a standard scratch wound was made. …"

Eliminations of dorsal projections in DOM and DOM-A downregulation were due to reduced number of sLNvs and decrease of PDF. حسب Zhenxing Liu (399809)

Prorocentin-5: A Cytotoxic Polyketide from the Benthic Marine Dinoflagellate <i>Prorocentrum lima</i> حسب Yunseok Choi (5625245)

الموضوعات:

Assessment of intratumoral CD3+ and CD8+ lymphocyte populations. حسب Gerik W. Tushoski-Alemán (17951809)