بدائل البحث:
_ we » _ e (توسيع البحث), _ fe (توسيع البحث)
_ ag » _ age (توسيع البحث), _ a (توسيع البحث), _ al (توسيع البحث)
decrease » decreased (توسيع البحث), increase (توسيع البحث)
_ we » _ e (توسيع البحث), _ fe (توسيع البحث)
_ ag » _ age (توسيع البحث), _ a (توسيع البحث), _ al (توسيع البحث)
decrease » decreased (توسيع البحث), increase (توسيع البحث)
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LDL-C Targets in Secondary Prevention: How Low Should We Go?
منشور في 2019"…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Fabrication of Ag<sub>2</sub>O/WO<sub>3</sub> based sensors for detection of hydrogen sulfide
منشور في 2022"…The results can be attributed to the decrease in the energy bandgap due to increasing the Ag content and the strong interaction between the Ag and WO<sub>3</sub> and silver to silver oxide transformation at low annealing temperatures. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the affected signaling networks were TGFβ1, SPP1, and ERK regulatory networks. Conclusions. We identified γ-secretase inhibitor (LY411575) as a potent regulator of osteoblastic differentiation of hBMSC that may be useful as a therapeutic option for treating conditions associated with ectopic bone formation.…"
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Visible Light Photocatalytic Activity of Ag/WO<sub>3</sub> Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark
منشور في 2022"…Ultraviolet–visible spectra analysis observed a large redshift in the absorbing band edge and decreased bandgap energy from 2.6 to 2.1 eV. Photocatalytic analysis at different concentrations of 1% Ag/WO<sub>3</sub> under visible light indicated a high degradation efficiency. …"
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…PP2A, GSK3β and Tau reside together in a complex, which facilitates their interaction and (dys)-function as has been reported for several neurological disorders. In this study we recorded maximum increase in total PP2A at 3 µM sodium selenate in a neuron cell line. …"
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
منشور في 2024"…Increasing condom use from 10 % to 50 % lowers NG prevalence among FSWs, clients, and their spouses from 12.2 % to 6.4 %, 1.2 % to 0.5 %, and 0.4 % to 0.2 %, respectively. …"
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Mechanisms behind the immediate effects of Roux-en-Y gastric bypass surgery on type 2 diabetes
منشور في 2013"…I.e., the largest possible decrease in glucose predicted by the model is smaller than reported decreases, and the model predicts no decrease whatsoever in glucose ×insulin, in contrast to large observed decreases in homeostatic model assessment insulin resistance (HOMA-IR). …"
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Antibacterial Properties of Polysulfone Membranes Blended with Arabic Gum
منشور في 2019"…A pronounced decrease in bacterial attachment was seen in the field emission scanning electron microscopy (FESEM) images for PS/AG membrane samples compared to both commercial (Microdyn-Nadir) and bare PS (without AG) membranes. …"
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Evaluation of the cementite morphology influence on the hydrogen induced crack nucleation and propagation path in carbon steels
منشور في 2022"…The ECCB tests were performed in H-free and two H charging steps with −1050 mV and −1550 mV charging potential versus Ag/AgCl reference electrode. The results show that both materials are resistant to crack initiation in the H-free condition while under −1050 mV charging, crack propagates through the grain boundaries in a tortuous path in spheroidite mi-crostructure and the lamellar microstructure displayed a higher strength with small cracks propagating through both the grain boundaries and the lamellas. …"
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Optoelectronic properties of highly porous silver oxide thin film
منشور في 2021"…The obtained results indicate the formation of mixed mesoporous Ag<sub>2</sub>O and AgO NW thin films. The Ag<sub>2</sub>O phase of silver oxide appears after 300 s of oxidation under the same conditions, while the optical transparency of the thin film decreases as plasma etching time increases. …"
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
منشور في 2024"…Gold (AuNPs) and silver (AgNPs) NPs are among the important nanoplatforms that received extensive attention recently for various biomedical applications. …"
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Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
منشور في 2023"…Additionally, IL-35 or THYO decreased TNF-α, NF-κB, IL-10, IL-6 and IFN-γ in contrast to the PAR control group. …"