HCV infection decreases L1 retrotransposition frequency. by Anja Schöbel (10668438)

Image1_Unexpected decrease of full-length prion protein in macaques inoculated with prion-contaminated blood products.TIFF by Nina Jaffré (15415058)

D-4F and L-5F attenuate hepatic triglyceride accumulation. by Kristine C. McGrath (8269155)

Subjects:

Genome-wide occurrence of 5mC and SNPs in Zt10. by Mareike Möller (5548745)

Subjects:

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> by Muhammad Saad Yousuf (20745168)

Spatial information of excitatory neurons in APP/PS1 mice are decreased in dCA1 and vCA1. by Udaysankar Chockanathan (18510288)

“…<p>(A) In dCA1, spatial information was decreased in APP/PS1 mice relative to C57BL/6 controls (mean ± std: C57BL/6 = 0.134 ± 0.050, APP/PS1 = 0.132 ± 0.054, p < 0.01, two-sided Wilcoxon rank-sum test, n_C57BL/6 = 229 units from 5 recording sessions, n_APP/PS1 = 124 units from 4 recording sessions). …”

Decreased fetal weight in CrryshRNA mice. by Manu Banadakoppa (9199271)

“…<p>Fetal and placental weights were measured at 17.5 dpc soon after euthanasia (n = 5–7), A) Average fetal weight was significantly reduced (<i>p</i> = 0.048) in CrryshRNA mice compared to control group B) Average placental weight was not different between the two groups C) Fetal-placental weight ratio was significantly decreased (<i>p</i> = 0.045) in Crry shRNA mice compared to control mice.…”

Data from all independent trials of adhesion assay (in Fig 5B–5C) and CP activity assay (in Fig 5D–5F). by Han Jiang (195350)

19606 decreases the luminal pH of the ACV during infection. by Jesus S. Distel (11250759)

Ce6 decreases the amount of TMV PQS5 upon photo-irradiation. by Congbao Xie (17599247)

Nicotine decreased Wnt5a expressions in SK-BR-3 cells. by Masanori A. Murayama (5774585)

Activating cAMP synthesis decreases liberation of propionyl-CoA from cholesterol. by Kaley M. Wilburn (12060476)

Increasing TPP side chain length decreases melanoma cell viability and clonogenic survival. by Kyle C. Kloepping (9928265)

“…A375 melanoma cells were treated with 0.25 μM, 0.5 μM, or 1.0 μM 5-, 8-, 10-, 12-,14-, or 16-TPP for (C) 24 h and (D) 48 h and analyzed for clonogenic survival (* represents when 12-, 14-, and 16-TPP were significant relative to 5-TPP and 8-TPP; Ψ represents when 10-TPP was significant relative to 5-TPP and 8-TPP; p < 0.05; n = 3 from 2 separate experiments; N = 6). …”

LuxR G37V has decreased DNA-binding activity. by Chelsea A. Simpson (9579303)

Nimodipine does not decrease markers of neuritic dystrophy in 5XFAD transgenic mice. by Katherine R. Sadleir (12035242)

“…Similarly, BACE1, LAMP1 and LC3B-II/ LC3B-I were also increased in nimodipine-treated 5XFAD compared to nimodipine treated non-transgenic mice, indicating that nimodipine did not decrease the accumulation of these dystrophic neurite marker proteins. …”

Video1_Unexpected decrease of full-length prion protein in macaques inoculated with prion-contaminated blood products.MP4 by Nina Jaffré (15415058)

Overexpression of CCP5A and CCP5B induced flagellum length decrease and cell cycle defects. by Louise Basmaciyan (4576624)

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation by Kairui Yue (11874403)

“…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …”

OIP5-AS1 binds to miR-145-5p. by Jingyan Yang (7120994)