Effect of melatonin (50 μM) on the TGF-β1 (10 ng/mL, 72 h)-mediated TGF-β1/Smad pathway and EMT in HBdSMCs. حسب Yang Zhang (30734)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades حسب Ihab Shawish (13015516)

الموضوعات:

Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production. حسب Bei Wang (116772)

Detection of the Challenging mutations at 1% VAF and 50 ng DNA input. حسب Lizhi Yu (12476136)

IC₅₀s data of antimalarials against controls. حسب Winnie Okore (14139712)

الموضوعات:

Passive transfer of humanized anti-NS1 mAb 33D2 into DENV-inoculated mice decreases viral titer and NS1 level in mouse sera. حسب Sen-Mao Tien (12481273)

Drugs IC₅₀s data during the study period. حسب Winnie Okore (14139712)

الموضوعات:

IODVA1 inhibits lamellipodia and circular dorsal ruffle (CDR) formation in MDA-MB-231 cells and decreases Rac activation. حسب Anjelika Gasilina (8566296)

Transcriptional and translational markers of syncytialization and biochemical differentiation are significantly decreased by rotenone. حسب O’Llenecia S. Walker (8486163)

SNPs IC₅₀s data at codon 876 during the study period. حسب Winnie Okore (14139712)

الموضوعات:

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation حسب Kairui Yue (11874403)

"…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …"

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation حسب Kairui Yue (11874403)

"…Representative inhibitor <b>35m</b> exhibits potent HDAC6 inhibitory activity with an IC₅₀ value of 0.019 μM. To our surprise, <b>35m</b> establishes significant improvement in the pharmacokinetic property with much higher AUC_0‑inf (10292 ng·h/mL) and oral bioavailability (93.4%) than hydroximic acid-based HDAC6 inhibitors Tubastatin A and ACY-1215. …"

Decreasing fluconazole susceptibility of clinical South African <i>Cryptococcus neoformans</i> isolates over a decade حسب Serisha D. Naicker (8648370)

The decrease in blood flow disrupts CV pruning. حسب Lin Wen (557398)

Tax expression is associated with decreased cellular motility. حسب Saumya Ramanayake (7879091)

Single-channel properties of L-AChRs activated by 10 μM ACh, 100 μM ACh or 100 μM levamisole in the absence and presence of terpenoids. حسب Guillermina Hernando (553795)

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> حسب Muhammad Saad Yousuf (20745168)

H& E staining investigation of CAM treated with native-orientin (5 μM), native-orientin (10 μM), NF-O (5 μM), and NF-O (10 μM). حسب Yashwanth Elumalai (21743452)

Association of polymorphic IC_50s versus wild<i>-</i>type at codon 876 in selected drugs tested. حسب Winnie Okore (14139712)

الموضوعات: