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Cytoskeletal Drugs Modulate Off-Target Protein Folding Landscapes Inside Cells
Published 2020“…The decreased compactness and folding stability of PGK could be explained by the decreased extent of crowding induced by these drugs. …”
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Macroscopic and histological assessment of colic tumor and inflammation in mice.
Published 2020Subjects: -
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Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif
Published 2022“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”
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