Parthenolide Derivatives as PKM2 Activators Showing Potential in Colorectal Cancer حسب Xingchen Liu (524190)

"…As a vital kinase in the glycolysis system, PKM2 is extensively expressed in colorectal cancer (CRC) to support the energy and biosynthetic needs. In this study, we designed a series of parthenolide (PTL) derivatives through a stepwise structure optimization, and an excellent derivate <b>29e</b> showed good activity on PKM2 (AC₅₀ = 86.29 nM) and displayed significant antiproliferative activity against HT29 (IC₅₀ = 0.66 μM) and SW480 (IC₅₀ = 0.22 μM) cells. …"

Temporal profiles of the key BO-NN features. حسب Julia Berezutskaya (9080269)

"…Right plot show the gradual decrease in the TM tuning for the features highlighted in <b>c</b> as well as the gradual increase in the temporal response profile (i.e. optimal shifts for the prediction of the key BO-NN features using Praat features shown in <b>a</b>). …"

Hypothesis that explains and predicts expansion of ages of KD due to decreased IgG levels. حسب Hiromi Yamaguchi (2396248)

Effect of atipamezole or efaroxan (0.5 mg·kg⁻¹) (Protocol 2). حسب Yoichiro Kitajima (4319455)

The inhibitory activity of the most active compounds against Glo-I enzyme with less than 50 µM. Their supportive corresponding docking values on two different protocols are display... حسب MohammedBashar Al-Qazzan (22439236)

Time dependent activation of the pulmonary inflammatory response. حسب Marc-Alexander Oestreich (13961375)

Trace-weighted images at b = 50 s/mm². حسب Tobit Führes (12647099)

Repeated LSPC treatment prolongs survival of and decreases PrP^Res accumulation in a subset of prion-infected mice. حسب Heather Bender (363996)

(a) Mycelial diameter (mm) determination on PDA plates, (b) Inhibition diameters, and (c) inhibition percentages of <i>Aspergillus flavus</i> treated with <i>U. epigea</i> extract... حسب Martha Cebile Jobe (21175426)

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Qualitative analyses of <i>U. epigea</i> bulb phytochemicals. حسب Martha Cebile Jobe (21175426)

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Nucleotide sequence alignment of aflatoxin genes <i>Nor, Omt</i>, <i>Ver</i> and <i>aflR</i> treated with <i>U. epigea</i> extract, Ag/ZnO (Biosynthesized and Conventional) nanopar... حسب Martha Cebile Jobe (21175426)

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Primer pairs and PCR conditions used for amplification of selected Aflatoxin PCR gene primer pairs and their condition. حسب Martha Cebile Jobe (21175426)

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DataSheet1_Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA HOXA11-As Expression.PDF حسب Ying Meng (327793)

Evolution of the frequency of <i>Loa loa</i> clinical symptoms over the 30-day follow-up period. حسب Luccheri Ndong Akomezoghe (18585684)

Olaparib reverses the oxLDL-mediated decrease in co-immunoprecipitation of IκBα with RelA or p50. حسب Khamis Mustafa (17941332)

"…Relative band densities from three independent experiments were analyzed. (A) OxLDL decreased co-immunoprecipitation of IκBα with both RelA and p50, and olaparib reversed the effect of oxLDL on the dissociation of IκBα with RelA and p50. …"

Adult schistosome motility and egg production are differentially affected by the nine N-acyl homoserine lactones. حسب Helen Whiteland (6743339)

Prorocentin-5: A Cytotoxic Polyketide from the Benthic Marine Dinoflagellate <i>Prorocentrum lima</i> حسب Yunseok Choi (5625245)

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Shows the 5′ region and the exons of the <i>C3</i> gene in the vertical line and the three new SNPs that we found by sequencing. حسب Yonghui Wang (287491)

The top ranked poisonous plants based on their LD50 and respondent scores. حسب Faisal Rasool (12530732)

Raw images of gels and blots. حسب Cao Wang (1500691)

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